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- 英文名：
IMR-32
- 库存：
1x10^6/瓶/支
- 供应商：
上海酶研
- 肿瘤类型：
详询
- 细胞类型：
人神经母细胞瘤细胞
- ATCC Number：
详询
- 品系：
IMR-32
- 组织来源：
人神经母细胞瘤细胞
- 相关疾病：
IMR-32
- 物种来源：
哺乳动物
- 免疫类型：
详询
- 细胞形态：
贴壁/悬浮
- 是否是肿瘤细胞：
详询
- 器官来源：
人神经母细胞瘤细胞
- 运输方式：
顺丰快递
- 年限：
5年
- 生长状态：
生长良好
IMR-32/IMR-32细胞系/IMR-32细胞株/IMR-32人神经母细胞瘤细胞
Cell line name IMR-32
Synonyms IMR 32; IMR32; Institute for Medical Research-32; GM03320; GM3320C; GM03320D; AG03320; AG3320
Accession CVCL_0346
Resource Identification Initiative To cite this cell line use: IMR-32 (RRID:CVCL_0346)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Caucasian.
Characteristics: Neuroblastic type (N-type).
Doubling time: 48 hours (PubMed=5459762); ~20 hours (ATCC=CCL-127); ~40-50 hours (DSMZ=ACC-165).
Omics: Array-based CGH.
Omics: Cell surface proteome.
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Misspelling: IMR-92; Note=Occasionally.
Misspelling: IRM-32; Note=Occasionally.
Derived from site: Metastatic; Abdomen; UBERON=UBERON_0000916.
HLA typing Source: PubMed=26589293
Class I
HLA-A A*24:02,24:02
HLA-B B*07:05,07:05
HLA-C C*05:01,12:03
Genome ancestry Source: PubMed=30894373
Origin % genome
African 0
Native American 0.56
East Asian, North 1.01
East Asian, South 0
South Asian 3.99
European, North 73.7
European, South 20.72
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
PubMed=7838528
Cheng N.C., Van Roy N., Chan A., Beitsma M., Westerveld A., Speleman F., Versteeg R.
Deletion mapping in neuroblastoma cell lines suggests two distinct tumor suppressor genes in the 1p35-36 region, only one of which is associated with N-myc amplification.
Oncogene 10:291-297(1995)
PubMed=8665486; DOI=10.1016/0304-3835(96)04250-4
Diccianni M.B., Chau L.S., Batova A., Vu T.Q., Yu A.L.-T.
The p16 and p18 tumor suppressor genes in neuroblastoma: implications for drug resistance.
Cancer Lett. 104:183-192(1996)
PubMed=9201287
Cinatl J. Jr., Hernaiz Driever P., Cinatl J., Ruckert D.G., Gumbel H.O., Rabenau H.F., Kornhuber B., Doerr H.-W.
Increased efficacy of aphidicolin killing of human neuroblastoma cells in vitro by encapsulation in liposomes.
Neoplasma 44:91-95(1997)
PubMed=9283597; DOI=10.1016/S0165-4608(96)00362-7
Van Roy N., Jauch A., Van Gele M., Laureys G., Versteeg R., De Paepe A., Cremer T., Speleman F.
Comparative genomic hybridization analysis of human neuroblastomas: detection of distal 1p deletions and further molecular genetic characterization of neuroblastoma cell lines.
Cancer Genet. Cytogenet. 97:135-142(1997)
PubMed=9516836; DOI=10.1016/S0959-8049(97)00319-5
Van Roy N., Laureys G., Van Gele M., Opdenakker G., Miura R., van der Drift P., Chan A., Versteeg R., Speleman F.
Analysis of 1;17 translocation breakpoints in neuroblastoma: implications for mapping of neuroblastoma genes.
Eur. J. Cancer 33:1974-1978(1997)
DOI=10.1007/0-306-46872-7_2
Thiele C.J.
Neuroblastoma.
(In book chapter) Human cell culture. Vol. 1. Cancer cell lines part 1; Masters J.R.W., Palsson B.O. (eds.); pp.21-53; Kluwer Academic Publishers; New York; USA (1999)
PubMed=11550280; DOI=10.1002/gcc.1174
Van Roy N., Van Limbergen H., Vandesompele J., Van Gele M., Poppe B., Salwen H.R., Laureys G., Manoel N., De Paepe A., Speleman F.
Combined M-FISH and CGH analysis allows comprehensive description of genetic alterations in neuroblastoma cell lines.
Genes Chromosomes Cancer 32:126-135(2001)
PubMed=11668190; DOI=10.1177/002215540104901105
Quentmeier H., Osborn M., Reinhardt J., Zaborski M., Drexler H.G.
Immunocytochemical analysis of cell lines derived from solid tumors.
J. Histochem. Cytochem. 49:1369-1378(2001)
PubMed=12210830; DOI=10.1002/jnr.10330
Yoshida S., Narita T., Taga T., Ohta S., Takeuchi Y.
Malignant rhabdoid tumor shows incomplete neural characteristics as revealed by expression of SNARE complex.
J. Neurosci. Res. 69:642-652(2002)
PubMed=12702577
Saito-Ohara F., Imoto I., Inoue J., Hosoi H., Nakagawara A., Sugimoto T., Inazawa J.
PPM1D is a potential target for 17q gain in neuroblastoma.
Cancer Res. 63:1876-1883(2003)
PubMed=15390183; DOI=10.1002/gcc.20096
Gebauer S., Yu A.L.-T., Omura-Minamisawa M., Batova A., Diccianni M.B.
Expression profiles and clinical relationships of ID2, CDKN1B, and CDKN2A in primary neuroblastoma.
Genes Chromosomes Cancer 41:297-308(2004)
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文献和实验*发表【中文论文】请标注：由上海酶研生物科技有限公司提供；
*发表【英文论文】请标注：From Shanghai EK-Bioscience Biotechnology Co., Ltd.
(human fibroblast), IMR-32 (human neuroblastoma), HL60 (human promyelocytic leukemia) and plant Arabidopsis thalina cells. When adapting the protocol to a different cell type, make sure you control each step by carefully checking the products
coactivator) (22) AAAGACUCCUUAGGACCGCUU Ishikawa Apaf-1 (31) 978-998 AATTGGTGCACTTTTACGTGA IMR90E1 ARC21 (1) AF006086 181-203 aagaatgaagctgataggacc Human HeLa ATR interacting protein (4) AF451323 254-274 AAGGTCCACAGATTATTAGAT Human HeLa ATR interacting
of SERMs. Science 295:2465-2468. 31. Lassus P, Opitz-Araya X, and Lazebnik Y. (2002). Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization. Science 297:1352-1354. 32. Scherr M, Battmer K, Winkler T, Heidenreich O
技术资料
