- 询价
- Cell Signaling Technology
- 3886
- USA
- 2025年08月09日
- W, IP, IHC-P
- H,M,R
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- 详细信息
- 文献和实验
- 技术资料
- 抗体英文名：
Glycogen Synthase (15B1) Rabbit mAb
- 抗原：
synthetic peptide corresponding to the sequence of human glycogen synthase
- 应用范围：
W, IP, IHC-P
- 保质期：
详见说明书
- 级别：
详见MSDS文件
- 供应商：
CST
- 适应物种：
H,M,R
- 库存：
大量
- 是否单克隆：
0
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting IP=Immunoprecipitation IHC-P=Immunohistochemistry (Paraffin)
Reactivity Key: H=Human M=Mouse R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Isotype |
|---|---|---|---|---|
| W IP IHC-P | H M R | Endogenous | 84 | Rabbit IgG |
| Protocols | |
|---|---|
| Specificity / Sensitivity | Glycogen Synthase (15B1) Rabbit mAb detects endogenous levels of total muscle and liver glycogen synthase protein. |
| Source / Purification | Glycogen Synthase (15B1) Rabbit mAb is produced by immunizing rabbits with a synthetic peptide corresponding to the sequence of human glycogen synthase. Western Blotting
Western blot analysis of extracts from various cell lines, using Glycogen Synthase (15B1) Rabbit mAb. IHC-P (paraffin)
Immunohistochemical analysis of paraffin-embedded human lung carcinoma, using Glycogen Synthase (15B1) Rabbit mAb. |
| Background | Glycogen synthase (GS) is a key enzyme in the regulation of glycogen synthesis. There are two main isoforms of mammalian GS: the muscle and the liver isoform (1-2). Muscle GS is expressed in several tissues, and liver GS appears to be tissue specific (3). GS is regulated by multi-site phosphorylation and by the binding of allosteric ligands. Phosphorylation leads to inactivation of GS, but activity is restored by the binding of the allosteric activator glucose-6-phosphate, which induces its dephosphorylation and activation (4). |
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
Rabbit Monoclonals Produced Using Epitomics® Technology, U.S. Patent No. 5,675,063. For Research Use Only. Not For Use In Diagnostic Procedures. |
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文献和实验(Ser645) expression, andincreases in the total level of β-catenin and glycogen synthase protein expression were observed . 1.1.1. Inorganic Elements as Inhibitors of GSK-3 Lithium was the first discovered GSK-3 inhibitor (15
h）即可。2. 修复大法——不仅仅是「煮一煮」微波炉修复：简单易行效果好，CST 推荐使用微波炉完成修复。合适的修复液：根据抗体说明书使用合适的修复液。用柠檬酸修复后，切片需浸泡在修复液中，自然冷却；而用 EDTA 修复后，切片可直接从修复缸中取出，直接进行下一步。注：使用不同的修复方式和不同生产商的抗体检测人肺癌组织中 EGFR 的表达。第一排为 CST 的 EGF Receptor (D38B1) XP® Rabbit mAb（#4267），EDTA 的修复方式明显优于柠檬酸盐及胃蛋白
v468. chapter 4 WNT 细胞通路 检测细胞GSK3活性与表达水平
., and Cohen, P. (1980) Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase. Eur. J. Biochem. 107, 519–527. 6. Cohen, P. and Goedert, M. (2004) GSK3 inhibitors: development
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