Acta Pharmaceutica Sinica B

简称Acta Pharm Sin B
大类医学
小类药学
ISSN2211-3835
EISSN2211-3843

最新文献

Aberrant astroglial Kir4.1 activation in the anterior cingulate cortex disrupts neuronal excitability and social behavior

PMID: 420392772026-04

A spatiotemporal selective bioinspired hybrid system engineered for preventing post-thrombolysis recurrence by inhibiting the ferroptosis pathway and reprogramming macrophages

PMID: 420392942026-04

In situ rewiring TAMs as annihilators by "Spark-relay" nanoinitiator with flexible reactant ratio for amplifying solid tumor immunotherapy

PMID: 420392882026-04

An oral immune enhancer with excellent biocompatibility for effectively strengthening body's immunity and treating cancer

PMID: 420392682026-04

A neurotensin receptor type 1-derived pepducin acts as a biased allosteric modulator to regulate target receptor function

PMID: 420392732026-04

Engineered apoptotic vesicle mimetics with tunable "eat-me" signaling precisely regulate tumor-associated macrophages for potentiating cancer immunotherapy

PMID: 420392782026-04

Engineered bacteria reprogram tumor microenvironment via cell senescence and neutrophil extracellular traps degradation

PMID: 420392792026-04

SIM: Discovery of novel RNA-targeting argonautes by self-iterative learning from scarce data

PMID: 420392712026-04

Deep eutectic solvents@enteric technology for orally delivering anticoagulant macromolecule drug

PMID: 420392952026-04

FTO-mediated m6A depletion drives prenatal prednisone exposure-induced cortical neurogenesis deficits and long-term anxiety-depression-like behaviors in offspring

PMID: 420392902026-04

GEMap: A comprehensive gene essentiality map for drug discovery

PMID: 420392992026-04

Isoalantolactone induces AML pyroptosis and potentiates α-PD-1 efficacy by targeting selenoprotein TXNRD1

PMID: 420392662026-04

A triple combination strategy for nasopharyngeal carcinoma: Aptamer-guided liposomal chemotherapy, engineered NK cells, and Fc-enhanced PD-L1 antibody therapy

PMID: 419097512026-03

Extracellular vesicles-derived hybrid biomimetic nanoplatforms camouflaged Golgi apparatus-targeted aggregation induced emission photosensitizer to elicit pyroptosis and immunogenic cell death for efficient antitumor photoimmunotherapy

PMID: 419097262026-03

Ferroptosis-based nano-assembly enhanced breast cancer therapy by inhibiting intratumor bacteria

PMID: 419097502026-03

Dichotomous role of CD47-SIRP α axis: Leveraging opposing functions in phagocytic resistance and transport assistance for enhanced nanocarrier biocompatibility and tumor penetration

PMID: 419097532026-03

TeroACT: A terpenoid bioactivity landscape and discovery platform

PMID: 419097372026-03

Paeoniflorin alleviates hypobaric hypoxia-triggered lung injury through targeting MEK2 to modulate ERK2-SGK1 signaling

PMID: 419097392026-03

bHLH130 mediates gibberellin signaling to regulate tanshinone biosynthesis in Salvia miltiorrhiza

PMID: 419097282026-03

PhenoModel: A multimodal phenotypic drug design foundation model for discovering novel potential inhibitors of multiple cancer cells

PMID: 419097442026-03