Inversion Mutation Analysis in Hemophilia A by Restriction Enzyme Analysis and Southern Blotting
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Intron 22 of the factor VIII gene contains a 9.5kb region of DNA that is repeated on at least two other locations telomeric to, and at least 500 kb from, the gene. These regions are termed intron 22 homologous regions (int22h) (1 ) and contain the Factor VIII associated gene (F8A).
