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        【求助】ki67为什么叫ki67?导师问的问题!

        丁香园论坛

        3453
        今天开题,导师问了个问题:ki67为什么叫ki67?当场傻住······恳请各位老师指教!谢谢。
        The Ki-67 protein was originally defined by the prototype monoclonal antibody Ki-67 (Gerdes et al., 1983),which was generated by immunizing mice with nuclei
        of the Hodgkin lymphoma cell line L428. The name is derived from the city of origin (Kiel) and the number of the original clone in the 96-well plate. Because the
        antigen was not initially characterized, it was referred to mainly as the Ki-67 antigen.

        ref:
        1. Gerdes J, Schwab U, Lemke H, Stein H. 1983. Production of a mouse
        monoclonal antibody reactive with a human nuclear antigen associated
        with cell proliferation. Int J Cancer 31:13–20.
        2. The Ki-67 Protein: From the Known and the UnknownJ. Cell.Physiol. 182:311–322, 2000.
        谢谢老师啦,长见识咯!
        求助中。。。。。。。。。。。。。。
        长见识了~
        果然都是有原因的,长见识了~
        学习了~

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