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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 保质期:
12个月
- 英文名:
Recombinant Mouse Ras-related protein Rab-10 (Rab10)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
10ug/20ug/50ug/100ug/200ug/500ug/1mg
| 规格: | 10ug | 产品价格: | ¥69.0 |
|---|---|---|---|
| 规格: | 20ug | 产品价格: | ¥139.0 |
| 规格: | 50ug | 产品价格: | ¥209.0 |
| 规格: | 100ug | 产品价格: | ¥349.0 |
| 规格: | 200ug | 产品价格: | ¥419.0 |
| 规格: | 500ug | 产品价格: | ¥559.0 |
| 规格: | 1mg | 产品价格: | ¥699.0 |
Research Areas
Signal TransductionUniprot ID
P61027Gene Names
Rab10Alternative Name(s)
Rab10; Ras-related protein Rab-10Lead Time
3-7 business daysOrganism
Mus musculus (Mouse)Source
E.coliExpression Region
1-200aaProtein Length
Full LengthTag Info
N-terminal 6xHis-taggedTarget Protein Sequence
MAKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKEPNSENVDISSGGGVTGWKSKCCMW
26.6 kDaPurity
Greater than 85% as determined by SDS-PAGE.Form
Lyophilized powder.If the size you ordered does not have lyophilized powder in stock, we will provide it in liquid formBuffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验PNAS:RAS 抑制剂又添一员,新型蛋白模拟物或为癌症治疗
13、RAB10、RAB14、RAB18、RAB5C 和 RAP1B)。序列分析表明,在 Sos 螺旋发夹结合区富集的 Ras 相关蛋白和其他 G 蛋白之间存在高度的序列相似性。图片来源:PNAS总的来说,该研究开发了一种 Sos 蛋白模拟物,它结合野生型和突变型 Ras,并对致癌 Ras 细胞具有选择性毒性作用。这种模拟物将为开发高 Ras 突变型癌症靶向抑制剂提供坚实的理论依据。延伸阅读该研究是同一团队十年前报道的跟进研究。图片来源:ScienceDirect 截图2011 年,Paramjit S
of complex and protein alone with the naked eye or a light microscope, crystals of covalently Cy5?labeled DNA can be directly used for X?ray diffraction data collection. Curr. Protoc. Nucleic Acid Chem. 46:7.15.1?7.15.8. © 2011 by John Wiley & Sons
组织并在那里生长。这一过程称为肿瘤的转移,9/10的患者都死于这种过程。 细胞癌变要有许多正常事件发生错误才会发生,因此在整个生命过程中癌症事实上是少见的,但是随着癌症的进展,突变在逐渐累积。儿童白血病是因较少的细胞突变引起。首先应从癌基因所产生的蛋白质开始。当癌基因被激活时,它便会促进细胞的生长和分裂。ras是1982年克隆出来的一种人类癌基因,大约在30%的人类癌症中是有突变的,也就是说它一直处于“开启”状态,不断地释放出生长信号,使得细胞疯狂地增殖。与ras情况相似的还有另外一种基因
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