- ￥4800
- Tanda
- 美国
- TD-21165
- 2025年10月25日
- ELISA, WB, IHC, IF
- 兔
- 脊椎动物
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A synthetic peptide near the C-terminus of human TP53 which includes the mutation of R282W.
- 形态：
液体
- 保存条件：
-20℃
- 克隆性：
多克隆
- 标记物：
FITC
- 适应物种：
脊椎动物
- 保质期：
24个月
- 抗原来源：
蛋白
- 目录编号：
TD-21165
- 级别：
科研级
- 库存：
999
- 供应商：
武汉天德
- 宿主：
兔
- 应用范围：
ELISA, WB, IHC, IF
- 浓度：
0.1 mg/ml
- 靶点：
R282W
- 抗体英文名：
Anti TP53(R282W) Rabbit Polyclonal Antibody
- 抗体名：
TP53(R282W) Polyclonal Antibody
- 规格：
100 μL
TP53(R282W) Polyclonal Antibody
| Cat. #: TD-21165 |
| Gene Symbol: TP53 |
| Description: Anti-TP53(R282W) Rabbit Polyclonal Antibody |
| Background: p53 protein acts as a tumor suppressor in many tumor types and induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Defects in TP53 are found in many types of cancers. |
| Immunogen: A synthetic peptide near the C-terminus of human TP53 which includes the mutation of R282W. |
| Applications: ELISA, WB, IHC, IF |
| Recommended Dilutions: ELISA: 1:1000-1:5000 WB: 1:1000-1:5000 IHC: 1:100-1:1000 |
| Concentration: 0.1 mg/ml |
| Host Species: Rabbit |
| Format: Liquid |
| Clonality: Polyclonal |
| Isotype: |
| Purity: Purified from serum |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Anti-TP53(R282W) antibody recognizes TP53(R282W) of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing. |
Western blot:
|
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
Science：直击肿瘤命门，Shibin Zhou 等开发靶向 TP53 突变的双特异性抗体
Q, R248W, R249S, R273C, R273H,R273L, R282W 进行了检测和验证。研究人员又对 28 例患者中分离出的 TILs 进行分析发现，有 11 例具有靶向 TP53 常见突变的 T 细胞反应，其中鉴定出的唯一共有的突变的 TP53 新表位是 HLA*02:01 R175H（HMTEVVRHC）。 图片来源：The Journal of clinical investigation 也就是说， HLA*02:01 R175H（HMTEVVRHC）这种新抗原突变并不
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