- ￥4800
- Tanda
- 美国
- TD-26425
- 2025年10月27日
- ELISA, WB, IHC
- Mouse
- 脊椎动物
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A synthetic peptide from the internal region of SMO which includes the mutation of A68V, human origin.
- 亚型：
lgG
- 形态：
液体
- 保存条件：
-20℃
- 克隆性：
单克隆
- 标记物：
FITC
- 适应物种：
脊椎动物
- 保质期：
24个月
- 抗原来源：
蛋白
- 目录编号：
TD-26425
- 级别：
科研级
- 库存：
999
- 供应商：
武汉天德
- 宿主：
Mouse
- 应用范围：
ELISA, WB, IHC
- 浓度：
1mg/ml
- 靶点：
A68V
- 抗体英文名：
Anti-SMO (A68V) mouse monoclonal antibody
- 抗体名：
SMO(A68V)
- 规格：
100 μL
SMO(A68V)
| Cat. #: TD-26425 |
| Size: 100 µL |
| Gene Symbol: SMO; MRD21 |
| Description: Anti-SMO(A68V) Mouse Monoclonal Antibody |
| Background: Smoothened is a protein that in humans is encoded by the SMO gene. Smoothened is a G protein-coupled receptor that is a component of the hedgehog signaling pathway and is conserved from flies to humans. It is the molecular target of the teratogen cyclopamine. SMO can function as an oncogene. Activating SMO mutations can lead to unregulated activation of the hedgehog pathway and cancer |
| Immunogen: A synthetic peptide from the internal region of SMO which includes the mutation of A68V, human origin. |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA: 1:1000-1:5000 WB: 1:500-1:1000 IHC: 1:50-1:100 |
| Concentration: 1 mg/ml |
| Host Species: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes A68V mutant, but not wild type SMO of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot:
|
Immunofluorescence:
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文献和实验[摘要]：随着全球新药研发重心东移，我国医药市场和临床试验的市场迅速发展，药物临床试验机构建设任重而道远，引入以现场管理组织（SMO）管理模式为代表的国际通行管理模式，建立完善的质量管理体系，保持良好的运作机制，提高试验的综合管理水平，保证临床试验的质量，使国内药物临床试验机构完成的试验数据得到国际认可，将有利于推动中国药物临床试验与国际接轨的进程。 [关键词]：药物临床试验机构；SMO管理模式；临床研究协调员CRC 2004年2月19日，国家食品
Spermine oxidase (SMO), the most recently characterized polyamine metabolic enzyme, catalyzes the direct back-conversion of spermine to spermidine in an FAD-dependent reaction that also yields the byproducts hydrogen peroxide (H2
Methods to Evaluate Alterations in Polyamine Metabolism Caused by Helicobacter pylori Infection
have revealed that H. pylori induces macrophage polyamine production by upregulation of the arginase 2/ornithine decarboxylase (ODC) metabolic pathway and enhances hydrogen peroxide synthesis through the activity of spermidine oxidase (SMO). In this chapter
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