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- 详细信息
- 技术资料
- 供应商:
武汉天德
- 库存:
999
- 靶点:
A68V
- 级别:
科研级
- 目录编号:
TD-26425
- 克隆性:
单克隆
- 抗原来源:
蛋白
- 保质期:
24个月
- 抗体英文名:
Anti-SMO (A68V) mouse monoclonal antibody
- 抗体名:
SMO(A68V)
- 标记物:
FITC
- 宿主:
Mouse
- 适应物种:
脊椎动物
- 免疫原:
A synthetic peptide from the internal region of SMO which includes the mutation of A68V, human origin.
- 亚型:
IgG
- 形态:
液体
- 应用范围:
ELISA, WB, IHC
- 保存条件:
-20℃
- 浓度:
1mg/ml
- 规格:
100μl
SMO(A68V)
| Cat. #: TD-26425 |
| Size: 100 µL |
| Gene Symbol: SMO; MRD21 |
| Description: Anti-SMO(A68V) Mouse Monoclonal Antibody |
| Background: Smoothened is a protein that in humans is encoded by the SMO gene. Smoothened is a G protein-coupled receptor that is a component of the hedgehog signaling pathway and is conserved from flies to humans. It is the molecular target of the teratogen cyclopamine. SMO can function as an oncogene. Activating SMO mutations can lead to unregulated activation of the hedgehog pathway and cancer |
| Immunogen: A synthetic peptide from the internal region of SMO which includes the mutation of A68V, human origin. |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA: 1:1000-1:5000 WB: 1:500-1:1000 IHC: 1:50-1:100 |
| Concentration: 1 mg/ml |
| Host Species: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes A68V mutant, but not wild type SMO of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot:
|
Immunofluorescence:
|
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SMO(A68V)
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