A synthetic peptide from the internal region of STK, which includes the mutation of P281L, human origin.
亚型:
lgG
形态:
液体
保存条件:
-20℃
克隆性:
单克隆
标记物:
FITC
适应物种:
脊椎动物
保质期:
24个月
抗原来源:
蛋白
目录编号:
TD-26158
级别:
科研级
库存:
999
供应商:
武汉天德
宿主:
Mouse
应用范围:
ELISA, WB, IHC
浓度:
1mg/ml
靶点:
STK11
抗体英文名:
Anti STK11 Mouse Monoclonal Antibody
抗体名:
STK11 Antibody
规格:
100 μL
STK11 Antibody
Cat. #: TD-26158
Size: 100 µL
Gene Symbol: STK11, LKB1, PJS, hLKB1
Description: Anti-STK11 Mouse Monoclonal Antibody
Background: Serine/threonine kinase 11 (STK11) also known as liver kinase B1 (LKB1) or renal carcinoma antigen NY-REN-19 is a kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response, and functions as a tumour suppressor. Recent studies have uncovered a large number of somatic mutations of the STK11 gene that are present in lung, cervical, breast, intestinal, testicular, pancreatic and skin cancer.
Immunogen: A synthetic peptide from the internal region of STK, which includes the mutation of P281L, human origin.
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity: Recognizes P281L mutated, but not wild type STK11 of vertebrates.
Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing
Immunofluorescence:
Immunofluorescence of cells expressing STK11 proteins with Anti-STK11 (P281L) antibody. HEK293T cells were transfected with pCDNA3-GFP-STK11 (WT) plasmid (left column) or pCDNA3-GFP-STK11 (P281L) plasmid (right column), then fixed and stained with Anti-STK11 (P281L) monoclonal antibody (Cat. #TD-26158).