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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
A synthetic peptide from the internal region of β-catenin which includes the mutation of G48D, human origin.
- 亚型:
lgG
- 形态:
液体
- 保存条件:
-20℃
- 克隆性:
单克隆
- 标记物:
FITC
- 适应物种:
脊椎动物
- 保质期:
24个月
- 抗原来源:
蛋白
- 目录编号:
TD-26166
- 级别:
科研级
- 库存:
999
- 供应商:
武汉天德
- 宿主:
Mouse
- 应用范围:
ELISA, WB, IF, IHC
- 浓度:
1mg/ml
- 靶点:
G48D
- 抗体英文名:
Antiβ-catenin(G48D) Mouse Monoclonal Antibody
- 抗体名:
β-Catenin(G48D)
- 规格:
100 μL
β-Catenin(G48D)
| Cat. #: TD-26166 |
| Gene Symbol: CTNNB1, CTNNB |
| Description: Anti-β-catenin(G48D) Mouse Monoclonal Antibody |
| Background: Beta-catenin (or β-catenin) is a protein that in humans is encoded by the CTNNB1 gene. β-catenin is a subunit of the cadherin protein complex and also acts as an intracellular signal transducer in the Wnt signaling pathway. Deregulation of beta-catenin signaling is an important event in the genesis of a number of malignancies, such as colon cancer, melanoma, hepatocellular carcinoma, ovarian cancer, endometrial cancer, medulloblastoma pilomatricomas, and prostate cancer. |
| Immunogen: A synthetic peptide from the internal region of β-catenin which includes the mutation of G48D, human origin. |
| Applications: ELISA, WB, IF, IHC |
| Recommended Dilutions: ELISA: 1:1000-1:5000 WB: 1:500-1:2000 IHC: 1:50-1:100 |
| Concentration: 1 mg/ml |
| Host Species: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes β-catenin (G48D), but not wild type β-catenin protein from vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot:
Immunofluorescence:
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文献和实验医生和球 看的文献较少,自己知道的只有wnt、PTEN等,请问还有哪些通路与β-catenin有关,有无类似的综述?谢谢! 狐狸renart 只知道wnt chuckdouble The canonical Wnt/beta-catenin signalling pathway. Barker N. Methods Mol Biol. 2008;468:5-15
【求助】关于β-catenin和细胞增殖的关系,急死了!!!
rainbubu 想研究β-catenin在某肿瘤中和细胞增殖和预后的关系,材料用存档的蜡块和冰冻,想用免疫组化来检测β-catenin的表达情况,然后想检测β-catenin的表达和细胞增殖的关系,能不能简单的看β-catenin和PCNA、ki-67之间的关系,有统计学意义就得出β-catenin和细胞增殖有相关性。 但是也不能说明细胞增殖就是β-catenin表达异常的结果啊 那么怎么才能说明β-catenin和细胞增殖的关系
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异丙基 -1-硫代β -D吡喃(型)半乳糖 isop-ropyl-1-thio-β -D-galactopyranoside 为 isopropyl-1-thio-β -D-galactopyranoside的缩写。是诱导大肠杆菌乳糖操纵子酶合成的强力诱导物。在培养基中加入该物 10-4 克分子时,即可通过存在于大肠杆菌细胞膜中的微量半乳糖苷渗透酶而被参入至细菌体内。通常诱导物质即根据这种通过操纵子的作用制造的β -半乳糖糖苷酶而被利用于代谢的。但 IPTG等不能
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