- 询价
- Agrisera
- 瑞典
- AS20 4455
- 2025年11月22日
- Optimal concentration should be evaluated by serial dilutions. Detects APP and Ab peptide by Western blot at 0.5 to 1 µg/ml.
- Rabbit
- Human, mouse, rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Synthetic peptide (aa 653-662 of human APP) or 1-10 of the 4kDa Amyloid- peptide generated by and secretases.
- 形态：
Liquid in PBS containing 0.02% sodium azide as a preservative.
- 保存条件：
Store at -20°C; make aliquots to avoid repeated fr
- 克隆性：
Polyclonal
- 适应物种：
Human, mouse, rat
- 级别：
分子生物学级
- 供应商：
Agrisera
- 宿主：
Rabbit
- 应用范围：
Optimal concentration should be evaluated by serial dilutions. Detects APP and Ab peptide by Western blot at 0.5 to 1 µg/ml.
- 靶点：
APP is an integral membrane protein found in many tissues and concentrated in the synapses of neurons. It is known as the precursor molecule generating amyloid beta (Aβ), and the amyloid fibrillar form is the primary component of amyloid plaques foun
- 抗体名：
APP | Amyloid Precursor Protein (N-term)
- 规格：
100 µg
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文献和实验Interaction of the Presenilins with the Amyloid Precursor Protein (APP)
the deposition of amyloid Aβ peptide. The latter is released from its cognate amyloid precursor protein (APP) by a two-step proteolytic conversion: first, proteolysis of APP by β-secretase, which releases the N-terminus of Aβ, and second, conversion
Phosphorylation of Amyloid Precursor Protein (APP) Family Proteins
including fly (4 ), nematode (5 ), and fish (6 ). In mammals, two APP-like genes, amyloid precursor-like protein 1 (APLP1) and 2 (APLP2), have been isolated (7 ,8 ). The amino acid sequences of these APP family proteins are highly conserved, especially
Using an Amyloid Precursor Protein (APP) Reporter to Characterize α-Secretase
Human genetic studies suggest decreasing amyloid peptide (Aβ) levels in the brain could alter the course of Alzheimer’s disease (AD) (1 -4 ). Proteolytic cleavages govern the level of Aβ generated from the amyloid precursor protein (APP). β
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