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文献和实验Secretion of Recombinant Human Insulin-Like Growth Factor I (IGF-I)
The development of efficient recombinant protein production processes can be a critical factor in whether or not a pharmaceutical therapeutic protein can enter human clinical trials and ultimately the marketplace. This is especially true
Generation of Functional Insulin-Producing Cells from Human Embryonic Stem Cells In Vitro
system, which could induce human ES cells to differentiate into functional insulin-producing cells. Activin A was first used in the initial stage to induce definitive endoderm lineage differentiation from human ES cells. And all-trans Retinoic Acid (RA) was then utilized
Assessment of Insulin Secretion in the Mouse
(insulin I∶II) ( 6 ). Fig. 1. Amino acid sequence of rat preproinsulin I. The superscripts indicate positions where amino acid differences exist in rat preproinsulin II and/or human preproinsulin relative to rat preproinsulin
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