CDN特约代理商|D-6462-0.01G Fenthion

CYP2D6-Dependent Bufuralol 1-Hydroxylation Assayed by Reversed-Phase lon-Pair High-Performance Liquid Chromatography with Fluorescence Detection

CYP2D6 is an enzyme that is subject to genetic polymorphism 1 . This P450 is absent in individuals with the poor metabolizer CYP2D6 phenotype 2 , 3 ), resulting in a substantially reduced capacity to metabolize a large number of clinically

尿液中儿茶酚胺和变肾上腺素进行快速、同步分析

和Waters Xevo TQD质谱的色谱柱结合使用，可获得具有出色线性、准确度和精密度的快速、稳定方法，并且能最大限度减少基质效应。   用含有0.1%抗坏血酸的甲醇配制多巴胺(DA)、去甲肾上腺素(NE)、肾上腺素(EP)、3-甲氧酪胺(3-MT)、变肾上腺素(MTN)和异丙肾上腺素(NMT)的标准品混合储液(10 µg/mL)，以防止氧化。混标储液由10 µg/mL D3-变肾上腺素、D3-异丙肾上腺素、D4-多巴胺、D6-肾上腺素和D6-去甲肾上腺素组成，也使用含有0.1%抗坏血酸的甲醇配制

凝胶过滤实验方法

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