Coronavirus spike重组蛋白|Recombinant Human coronavirus(HCoV-OC43)Spike Protein(S1+S2 ECD, His Tag)
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Coronavirus spike重组蛋白|Recombinant Human coronavirus(HCoV-OC43)Spike Protein(S1+S2 ECD, His Tag)

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  • ¥5820
  • Sino Biological已认证
  • 北京
  • 40607-V08B
  • 2025年08月12日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      -20℃ to -80℃

    • 保质期

      12个月

    • 英文名

      Recombinant Human coronavirus(HCoV-OC43)Spike Protein(S1+S2 ECD, His Tag)

    • 库存

      99

    • 供应商

      北京义翘神州科技股份有限公司

    • 规格

      100.00 µg

    Human coronavirus (HCoV-OC43) Spike Protein (S1+S2 ECD, His Tag): 产品信息

    纯度
    > 85 % as determined by SDS-PAGE.
    内毒素
    < 1.0 EU per μg protein as determined by the LAL method.
    生物活性
    Testing in progress
    蛋白构建
    A DNA sequence encoding the human coronavirus (HCoV-OC43) spike protein (S1+S2 ECD) (AVR40344.1) (Met1-Pro1304) was expressed with a polyhistidine tag at the C-terminus.
    表达宿主
    Baculovirus-Insect Cells
    种属
    HCoV-OC43
    预测 N 端
    Phe 13
    分子量
    The recombinant human coronavirus (HCoV-OC43) spike protein (S1+S2 ECD, His Tag) consists of 1303 amino acids and predicts a molecular mass of 145.1 kDa.

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    图标文献和实验
    该产品被引用文献
    1, Yu J, et al. Direct activation of the alternative complement pathway by SARS-CoV-2 spike proteins is blocked by factor D inhibition.Blood, PubMed ID: 32877502
    2, Liu T, et al. Quantification of antibody avidities and accurate detection of SARS-CoV-2 antibodies in serum and saliva on plasmonic substrates.Nature biomedical engineering, PubMed ID: 33122853
    3, Anderson EM, et al. Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection.medRxiv : the preprint server for health sciences, PubMed ID: 33200143
    4, Sakharkar M, et al. Prolonged evolution of the human B cell response to SARS-CoV-2 infection.Science immunology, PubMed ID: 33622975
    5, Klausberger M, et al. A comprehensive antigen production and characterisation study for easy-to-implement, specific and quantitative SARS-CoV-2 serotests.EBioMedicine, PubMed ID: 33906067
    6, Ravindran R, et al. Immune response dynamics in COVID-19 patients to SARS-CoV-2 and other human coronaviruses.PloS one, PubMed ID: 34242356
    7, Jennewein MF, et al. Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects.Cell reports, PubMed ID: 34237283
    8, Natarajan H, et al. Markers of Polyfunctional SARS-CoV-2 Antibodies in Convalescent Plasma.mBio, PubMed ID: 33879585
    9, Wratil PR, et al. Evidence for increased SARS-CoV-2 susceptibility and COVID-19 severity related to pre-existing immunity to seasonal coronaviruses.Cell reports, PubMed ID: 34932974
    10, Lin CY, et al. Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response.Cell host & microbe, PubMed ID: 34965382
    11, Narowski TM, et al. SARS-CoV-2 mRNA vaccine induces robust specific and cross-reactive IgG and unequal neutralizing antibodies in naive and previously infected people.Cell reports, PubMed ID: 35090596
    12, Lederer K, et al. Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals.Cell, PubMed ID: 35202565
    13, Pattinson D, et al. A Novel Method to Reduce ELISA Serial Dilution Assay Workload Applied to SARS-CoV-2 and Seasonal HCoVs.Viruses, PubMed ID: 35336970
    14, Minervina AA, et al. SARS-CoV-2 antigen exposure history shapes phenotypes and specificity of memory CD8 T cells.medRxiv : the preprint server for health sciences, PubMed ID: 34341799
    15, Lanz TV, et al. Limited Neutralization of Omicron by Antibodies from the BNT162b2 Vaccination against SARS-CoV-2.Research square, PubMed ID: 35441169
    16, Minervina AA, et al. SARS-CoV-2 antigen exposure history shapes phenotypes and specificity of memory CD8+ T cells.Nature immunology, PubMed ID: 35383307
    17, Sun X, et al. Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2.Nature microbiology, PubMed ID: 35773398
    18, Anderson EM, et al. SARS-CoV-2 infections elicit higher levels of original antigenic sin antibodies compared with SARS-CoV-2 mRNA vaccinations.Cell reports, PubMed ID: 36261003
    19, López-Muñoz AD, et al. Cell Surface Nucleocapsid Protein Expression: A Betacoronavirus Immunomodulatory Strategy.bioRxiv : the preprint server for biology, PubMed ID: 36993159
    20, Ravindran R, et al. Dynamics of temporal immune responses in nonhuman primates and humans immunized with COVID-19 vaccines.PloS one, PubMed ID: 37856429
    21, Dos Santos Alves RP, et al. Human coronavirus OC43-elicited CD4+ T cells protect against SARS-CoV-2 in HLA transgenic mice.Nature communications, PubMed ID: 38278784
    22, Sibille G, et al. The Novel A-Type Proanthocyanidin-Rich Phytocomplex SP4™ Acts as a Broad-Spectrum Antiviral Agent against Human Respiratory Viruses.International journal of molecular sciences, PubMed ID: 39000477
    23, Li Z, et al. Affinity-independent memory B cell origin of the early antibody-secreting cell response in naive individuals upon SARS-CoV-2 vaccination.Immunity, PubMed ID: 39168129
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    Coronavirus spike重组蛋白|Recombinant Human coronavirus(HCoV-OC43)Spike Protein(S1+S2 ECD, His Tag)
    ¥5820