NMDA

Immunocytochemistry of NMDA Receptors

This chapter covers the major immunocytochemical methods used in our laboratory for NMDA receptor localization. There are three methods: pre-embedding immunoperoxidase for light microscopy (LM), the same for electron microscopy (EM

Redox Sensitivity of NMDA Receptors

The redox modulatory sites of the NMDA receptor consist of critical cysteine residues, which when chemically reduced, increase the magnitude of NMDA-evoked responses. In contrast, after oxidation, NMDA-evoked responses are decreased in size

Engineering the NMDA Receptor Channel Lining

Neurotransmitter-gated channels, such as the NMDA receptor, are oligomeric membrane proteins assembled from multiple homologous subunits organized around a central ion-conducting pore (1 ,2 ). A major effort is directed toward understanding