CAY10435

一种选择性且强效的大鼠FAA酰胺水解酶（FAAH）抑制剂（Ki=0.57nM）；在筛选血清水解酶家族酶时，其IC50值分别为0.81nM、83nM和50µM，针对FAAH、TGH和未表征水解酶（KIAA1363）。A selective, potent inhibitor of rat FAAH (Ki = 0.57 nM); exhibited IC50 values of 0.81, 83 nM, and 50 µM for FAAH, TGH, and an uncharacterized hydrolase (KIAA1363), respectively, when screened against the serine hydrolase family of enzymes.