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文献和实验Measurement of Activities of Cyclobutane-Pyrimidine-Dimer and (6-4)-Photoproduct Photolyases
The adverse biological consequences of unrepaired toxic UV-B-induced photoproducts in DNA, mostly cyclobutane pyrimidine dimers (CPDs) and pyrimidine-(6-4′)-pyrimidone photoproducts [(6-4) photoproducts; (6-4)PPs], are touched on in Chapters
Measuring the Formation and Repair of UV Photoproducts by Ligation-Mediated PCR
] photoproducts; [6-4]PPs). In addition, UV irradiation produces, although at significantly lower levels, purine dimers, a photoproduct at TpA sequences, and pyrimidine monoadducts, such as photohydrates (3 ). CPDs are formed between the 5,6 bonds of two adjacent
Monitoring Removal of Cyclobutane Pyrimidine Dimers in Arabidopsis
] photoproducts; [6-4]PPs), in about the same proportions—70–80% CPDs, 20–30% (6-4)PPs—as does UV-B radiation, so the former is frequently used in laboratory situations. Other photoproducts account for 1–2% at most of UV photoproducts, so CPDs and (6-4)PPs
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