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细胞线粒体分离试剂盒

价格￥453

品牌碧云天
货号C3601
更新日期2025年09月09日

上海碧云天生物技术股份有限公司

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详细信息
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文献和实验
技术资料

保存条件：
-20℃
供应商：
上海碧云天生物技术有限公司
规格：
50-100次

细胞线粒体分离试剂盒(Cell Mitochondria Isolation Kit)是用于快速便捷地分离培养细胞线粒体的试剂盒。
本试剂盒在分离线粒体的同时可以获得去除线粒体的细胞浆蛋白，可用于研究细胞色素c等线粒体蛋白向胞浆的释放。
使用本试剂盒分离获得的线粒体纯度较高，并且绝大部分分离获得的线粒体都含有完整的内膜和外膜，并具有线粒体的生理功能。因此本试剂盒分离得到的线粒体可以用于线粒体的生理功能等方面的研究。例如可以使用碧云天的C2006 线粒体膜电位检测试剂盒(JC-1)测定分离得到的线粒体的膜电位。
本试剂盒分离得到的线粒体也可以被试剂盒中的线粒体裂解液或其它适当裂解液裂解后用于SDS-PAGE、Western、双向电泳等蛋白分析。
本试剂盒提供了线粒体制备过程中匀浆程度的重要判断指标，即台盼蓝染色，使分离得到的线粒体的质量更加有保证。台盼蓝染色液为选用试剂，在实验条件成熟后可以不必使用。
本试剂盒提供了蛋白酶抑制剂PMSF，使匀浆时蛋白酶的活性被适当抑制，这样在获得线粒体的同时还可以获得有时有用的去除了大量线粒体的蛋白，在进行蛋白或酶活分析时可以作为对照。
如果每个样品的细胞数量为2000-5000万，本试剂盒可以处理50-100个样品。
包装清单：

产品编号	产品名称	包装
C3601-1	线粒体分离试剂	125ml
C3601-2	台盼蓝染色液	10ml
C3601-3	线粒体储存液	15ml
C3601-4	线粒体裂解液	15ml
C3601-5	PMSF(晶体)	For 1.5ml 100mM
C3601-6	PMSF(溶剂)	1.5ml
—	说明书	1份

保存条件：
-20℃保存，一年有效。其中台盼蓝染色液也可以4℃保存，PMSF(晶体)和PMSF(溶剂)在配制成100mM PMSF溶液前可以室温保存。
注意事项：
试剂盒中的试剂对于不同的实验目的不必全部使用。
如果不是用于制备线粒体蛋白样品，线粒体分离试剂和线粒体裂解液中不必加入PMSF。
如果用于制备线粒体蛋白样品，线粒体分离试剂和线粒体裂解液中需添加PMSF。PMSF一定要在线粒体分离试剂或线粒体裂解液加入到样品中前2-3分钟内加入，以免PMSF在水溶液中很快失效。
分离线粒体的所有步骤均需在冰上或4℃进行，所用溶液需冰浴或4℃预冷。
通常在分离线粒体时前后两次离心速度选取600g和11,000g，如果希望纯度更高，但对线粒体的得率要求不高，前后两次离心速度可以采用1000g和3500g。
使用本试剂盒中的线粒体储存液稀释或储存的线粒体样品应及时使用，以免线粒体膜电位受影响。如果不能及时使用，建议在-80℃保存。冻存后的线粒体样品不推荐用于膜电位的检测，但可以用线粒体蛋白或核酸的相关检测。
如果出现本试剂盒中线粒体储存液不够用的情况，可以单独订购线粒体储存液(C3609)。
台盼蓝与PMSF对人体有毒，操作时请特别小心，并注意有效防护以避免直接接触人体或吸入体内。
Bradford法蛋白浓度测定试剂盒(P0006)、Bradford蛋白浓度测定试剂盒(去垢剂兼容型)(P0006C)和BCA蛋白浓度测定试剂盒(P0009/P0010/P0010S/P0011/P0012/P0012S)可以向碧云天订购。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
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72. Liu D, Yi B, Liao Z, Tang L, Yin D, Zeng S, Yao J, He M.

14-3-3γ protein attenuates lipopolysaccharide-induced cardiomyocytes injury through the Bcl-2 family/mitochondria pathway.

Int Immunopharmacol. 2014 Aug;21(2):509-15.(IF 3.943)

73. Li Y, Zhang B, Huang K, He X, Luo Y, Liang R, Luo H, Shen XL, Xu W.

Mitochondrial proteomic analysis reveals the molecular mechanisms underlying reproductive toxicity of zearalenone in MLTC-1 cells.

Toxicology. 2014 Oct 3;324:55-67.(IF 4.099)

74. He Y, Wu YT, Huang C, Meng XM, Ma TT, Wu BM, Xu FY, Zhang L, Lv XW, Li J.

Inhibitory effects of long noncoding RNA MEG3 on hepatic stellate cells activation and liver fibrogenesis.

BBA-BIOMEMBRANES. 2014 Nov;1842(11):2204-15.(IF 3.411)

75. Zhou J, Xi C, Wang W, Fu X, Jinqiang L, Qiu Y, Jin J, Xu J, Huang Z.

Triptolide-induced oxidative stress involved with Nrf2 contribute to cardiomyocyte apoptosis through mitochondrial dependent pathways.

Toxicol Lett. 2014 Nov 4;230(3):454-66.(IF 3.569)

76. Zhou Y, Zhao W, Xie G, Huang M, Hu M, Jiang X, Zeng D, Liu J, Zhou H, Chen H, Wang GH, Zhang XK.

Induction of Nur77-dependent apoptotic pathway by a coumarin derivative through activation of JNK and p38 MAPK.

Carcinogenesis. 2014 Dec;35(12):2660-9.(IF 4.603)

77. Wu ZJ, Yu J, Fang QJ, Wang RX, Lian JB, He RL, Jiao HX, Lin MJ.

Sodium Ferulate Prevents Daunorubicin-Induced Apoptosis in H9c2 Cells via Inhibition of the ERKs Pathway.

CELL PHYSIOL BIOCHEM. 2015;36(6):2121-36.(IF 5.5)

78. Yan J, Liu XH, Han MZ, Wang YM, Sun XL, Yu N, Li T, Su B, Chen ZY.

Blockage of GSK3β-mediated Drp1 phosphorylation provides neuroprotection in neuronal and mouse models of Alzheimer's disease.

Neurobiol Aging. 2015 Jan;36(1):211-27.(IF 4.347)

79. Deng S, Tang S, Zhang S, Zhang C, Wang C, Zhou Y, Dai C, Xiao X.

Furazolidone induces apoptosis through activating reactive oxygen species-dependent mitochondrial signaling pathway and suppressing PI3K/Akt signaling pathway in HepG2 cells.

Food Chem Toxicol. 2015 Jan;75:173-86.(IF 4.679)

80. Wen X, Zhou J, Zhang D, Li J, Wang Q, Feng N, Zhu H, Song Y, Li H, Bai C.

Denatonium inhibits growth and induces apoptosis of airway epithelial cells through mitochondrial signaling pathways.

RESP RES . 2015 Feb 5;16:13.(IF 3.751)

81. Li X, Liu X, Xu Y, He Y, Liu J, Xie M.

Expression profile of apoptotic and proliferative proteins in hypoxic HUVEC treated with statins.

Int J Oncol. 2015 Feb;46(2):677-84.(IF 3.899)

82. Huang G, Mao J, Ji Z, Ailati A.

Stachyose-induced apoptosis of Caco-2 cells via the caspase-dependent mitochondrial pathway.

Food Funct. 2015 Mar;6(3):765-71.(IF 4.171)

83. Chu B, Liu F, Li L, Ding C, Chen K, Sun Q, Shen Z, Tan Y, Tan C, Jiang Y.

A benzimidazole derivative exhibiting antitumor activity blocks EGFR and HER2 activity and upregulates DR5 in breast cancer cells.

Cell Death Dis. 2015 Mar 12;6:e1686.(IF 6.304)

84. Zhang Q, Cheng G, Qiu H, Zhu L, Ren Z, Zhao W, Zhang T, Liu L.

The p53-inducible gene 3 involved in flavonoid-induced cytotoxicity through the reactive oxygen species-mediated mitochondrial apoptotic pathway in human hepatoma cells.

Food Funct. 2015 May;6(5):1518-25.(IF 4.171)

85. Sun W, Zhang X, Ding X, Li H, Geng M, Xie Z, Wu H, Huang M.

Lactate Dehydrogenase B Is Associated with the Response to Neoadjuvant Chemotherapy in Oral Squamous Cell Carcinoma.

PLoS One. 2015 May 14;10(5):e0125976.(IF 2.74)

86. Zheng G, Lyu J, Liu S, Huang J, Liu C, Xiang D, Xie M, Zeng Q.

Silencing of uncoupling protein 2 by small interfering RNA aggravates mitochondrial dysfunction in cardiomyocytes under septic conditions.

Int J Mol Med. 2015 Jun;35(6):1525-36.(IF 3.098)

87. Guo Z, Li CS, Wang CM, Xie YJ, Wang AL.

CSE/H2S system protects mesenchymal stem cells from hypoxia and serum deprivation induced apoptosis via mitochondrial injury, endoplasmic reticulum stress and PI3K/Akt activation pathways.

Mol Med Rep. 2015 Aug;12(2):2128-34.(IF 2.1)

88. Lai W, Zheng Z, Zhang X, Wei Y, Chu K, Brown J, Hong G, Chen L.

Salidroside-Mediated Neuroprotection is Associated with Induction of Early Growth Response Genes (Egrs) Across a Wide Therapeutic Window.

Neurotox Res. 2015 Aug;28(2):108-21.(IF 2.992)

89. Wang J, Gao Q, Wang D, Wang Z, Hu C.

Metformin inhibits growth of lung adenocarcinoma cells by inducing apoptosis via the mitochondria mediated pathway.

Oncol Lett. 2015 Sep;10(3):1343-1349.(IF 2.311)

90. Lu M, Sun L, Zhou J, Zhao Y, Deng X.

Dihydroartemisinin-Induced Apoptosis is Associated with Inhibition of Sarco/Endoplasmic Reticulum Calcium ATPase Activity in Colorectal Cancer.

Cell Biochem Biophys. 2015 Sep;73(1):137-45.(IF 2.073)

91. Cai XY, Xia Y, Yang SH, Liu XZ, Shao ZW, Liu YL, Yang W, Xiong LM.

Ropivacaine-and bupivacaine-induced death of rabbit annulus fibrosus cells in vitro: involvement of the mitochondrial apoptotic pathway.

OSTEOARTHR CARTILAGE. 2015 Oct;23(10):1763-75.(IF 4.793)

92. Cao L, Chen J, Li M, Qin YY, Sun M, Sheng R, Han F, Wang G, Qin ZH.

Endogenous level of TIGAR in brain is associated with vulnerability of neurons to ischemic injury.

Neurosci Bull. 2015 Oct;31(5):527-40.(IF 4.326)

93. Gong Y, Ni ZH, Zhang X, Chen XH, Zou ZM.

Valproic Acid Enhances the Anti-tumor Effect of (-)-gossypol to Burkitt Lymphoma Namalwa Cells.

Biomed Environ Sci. 2015 Oct;28(10):773-7.(IF 2.656)

94. Yang J, Yao S.

JNK-Bcl-2/Bcl-xL-Bax/Bak Pathway Mediates the Crosstalk between Matrine-Induced Autophagy and Apoptosis via Interplay with Beclin 1.

Int J Mol Sci. 2015 Oct 27;16(10):25744-58.(IF 4.556)

95. ang P, Fu S, Cao Z, Liao H, Huo Z, Pan Y, Zhang G, Gao A, Zhou Q.

Oroxin B selectively induces tumor-suppressive ER stress and concurrently inhibits tumor-adaptive ER stress in B-lymphoma cells for effective anti-lymphoma therapy.

TOXICOL APPL PHARM . 2015 Oct 15;288(2):269-79.(IF 3.616)

96. Feng B, Qiu L, Ye C, Chen L, Fu Y, Sun W.

Exposure to a 50-Hz magnetic field induced mitochondrial permeability transition through the ROS/GSK-3β signaling pathway.

Int J Radiat Biol. 2016;92(3):148-55.(IF 2.368)

97. Dong WQ, Chao M, Lu QH, Chai WL, Zhang W, Chen XY, Liang ES, Wang LB, Tian HL, Chen YG, Zhang MX.

Prohibitin overexpression improves myocardial function in diabetic cardiomyopathy.

ONCOTARGET. 2016 Jan 5;7(1):66-80.(IF 5.168)

98. Tan G, Liu D, Pan F, Zhao J, Li T, Ma Y, Shen B, Lyu J.

His-87 ligand in mitoNEET is crucial for the transfer of iron sulfur clusters from mitochondria to cytosolicaconitase.

BIOCHEM BIOPH RES CO. 2016 Jan 29;470(1):226-32.(IF 2.985)

99. Li M, Song M, Ren LM, Xiu CY, Liu JY, Zhu YZ, Li YF.

AlCl3 induces lymphocyte apoptosis in rats through the mitochondria-caspase dependent pathway.

Environ Toxicol. 2016 Apr;31(4):385-94.(IF 3.118)

100. Jin F, Qiao C, Luan N, Li H.

Lentivirus-mediated PHLDA2 overexpression inhibits trophoblast proliferation, migration and invasion, and induces apoptosis.

Int J Mol Med. 2016 Apr;37(4):949-57.(IF 3.098)

101. Li Z, Liu X, Wang L, Wang Y, Du C, Xu S, Zhang Y, Wang C, Yang C.

The role of PGC-1α and MRP1 in lead-induced mitochondrial toxicity in testicular Sertoli cells.

Toxicology. 2016 Apr 29;355-356:39-48.(IF 4.099)

102. Zhao FL, Qiao PF, Yan N, Gao D, Liu MJ, Yan Y.

Hydrogen Sulfide Selectively Inhibits γ-Secretase Activity and Decreases Mitochondrial Aβ Production in Neurons from APP/PS1 Transgenic Mice.

Neurochem Res. 2016 May;41(5):1145-59.(IF 3.038)

103. Kong F, Wang H, Guo J, Peng M, Ji H, Yang H, Liu B, Wang J, Zhang X, Li S.

Hsp70 suppresses apoptosis of BRL cells by regulating the expression of Bcl-, cytochrome C, andcaspase 8/3.

IN VITRO CELL DEV-AN. 2016 May;52(5):568-75.(IF 1.665)

104. Yu H, Guan Q, Guo L, Zhang H, Pang X, Cheng Y, Zhang X, Sun Y.

Gypenosides alleviate myocardial ischemia-reperfusion injury via attenuation of oxidative stress andpreservation of mitochondrial function in rat heart.

CELL STRESS CHAPERON. 2016 May;21(3):429-37.(IF 2.892)

105. Zhao FL, Qiao PF, Yan N, Gao D, Liu MJ, Yan Y.

Hydrogen Sulfide Selectively Inhibits γ-Secretase Activity and Decreases Mitochondrial Aβ Production inNeurons from APP/PS1 Transgenic Mice.

Neurochem Res. 2016 May;41(5):1145-59.(IF 3.038)

106. Wang J, Cai J, Huang Y, Ke Q, Wu B, Wang S, Han X, Wang T, Wang Y, Li W, Lao C, Song W, Xiang AP.

Nestin regulates proliferation and invasion of gastrointestinal stromal tumor cells by altering mitochondrial dynamics.

Oncogene. 2016 Jun;34:3139-50.(IF 7.971)

107. Wang XD, Li CY, Jiang MM, Li D, Wen P, Song X, Chen JD, Guo LX, Hu XP, Li GQ, Zhang J, Wang CH, He ZD.

Induction of apoptosis in human leukemia cells through an intrinsic pathway by cathachunine, a uniquealkaloid isolated from Catharanthus roseus.

Phytomedicine. 2016 Jun 1;23(6):641-53.(IF 4.268)

108. Huang JY, Yuan YH, Yan JQ, Wang YN, Chu SF, Zhu CG, Guo QL, Shi JG, Chen NH.

20C, a bibenzyl compound isolated from Gastrodia elata, protects PC12 cells against rotenone-inducedapoptosis via activation of the Nrf2/ARE/HO-1 signaling pathway.

Acta Pharmacol Sin. 2016 Jun;37(6):731-40.(IF 5.064)

109. Wu L, Bao K, Song R, Wang D, Zhang L, Wang W, Zhang W, Bin W.

Development of Novel Erythromycin Derivatives with Inhibitory Activity against Proliferation of TumorCells.

PLoS One. 2016 Jul 22;11(7):e0159503.(IF 2.74)

110. Wei C, Li H, Wang Y, Peng X, Shao H, Li H, Bai S, Xu C.

Exogenous spermine inhibits hypoxia/ischemia-induced myocardial apoptosis via regulation ofmitochondrial permeability transition pore and associated pathways.

EXP BIOL MED. 2016 Aug;241(14):1505-15.(IF 3.139)

111. Yang Y, Wang W, Xiong Z, Kong J, Qiu Y, Shen F, Huang Z.

Activation of SIRT3 attenuates triptolide-induced toxicity through closing mitochondrial permeabilitytransition pore in cardiomyocytes.

Toxicol In Vitro. 2016 Aug;34:128-37.(IF 2.959)

112. Li W, Wang Q, Du M, Ma X, Wu L, Guo F, Zhao S, Huang F, Wang H, Qin G.

Effects of overexpressing FoxO1 on apoptosis in glomeruli of diabetic mice and in podocytes cultured inhigh glucose medium.

BIOCHEM BIOPH RES CO. 2016 Sep 16;478(2):612-7.(IF 2.985)

113. Zhang GM, Deng MT, Zhang YL, Fan YX, Wan YJ, Nie HT, Wang ZY, Wang F, Lei ZH.

Effect of PGC-1α overexpression or silencing on mitochondrial apoptosis of goat luteinized granulosa cells.

J Bioenerg Biomembr. 2016 Oct;48(5):493-507.(IF 2.524)

114. Wo L, Lu D, Gu X.

Knockdown of miR-182 promotes apoptosis via regulating RIP1 deubiquitination in TNF-α-treated triple-negative breast cancer cells.

TUMOR BIOL . 2016 Oct;37(10):13733-13742.(IF 3.65)

115. Li Q, Tang Y, Qin J, Yi L, Yang Y, Wang J, He J, Su Q, Tan H.

Subcellular localization of DJ-1 in human HL-60 leukemia cells in response to diallyl disulfide treatment.

Mol Med Rep. 2016 Nov;14(5):4666-4672.(IF 2.1)

116. Teng H, Huang Q, Chen L.

Inhibition of cell proliferation and triggering of apoptosis by agrimonolide through MAP kinase (ERK andp38) pathways in human gastric cancer AGS cells.

Food Funct. 2016 Nov 9;7(11):4605-4613.(IF 4.171)

117. Song E, Tang S, Xu J, Yin B, Bao E, Hartung J.

Lenti-siRNA Hsp60 promote bax in mitochondria and induces apoptosis during heat stress.

BIOCHEM BIOPH RES CO. 2016 Dec 2;481(1-2):125-131.(IF 2.985)

118. Gong L, Di C, Xia X, Wang J, Chen G, Shi J, Chen P, Xu H, Zhang W.

AKT/mTOR signaling pathway is involved in salvianolic acid B-induced autophagy and apoptosis inhepatocellular carcinoma cells.

Int J Oncol. 2016 Dec;49(6):2538-2548.(IF 3.899)

119. Liu Z, Gao L, Wang P, Xie Z, Cen S, Li Y, Wu X, Wang L, Su H, Deng W, Wang S, Li D, Li J, Ouyang Y, Wu Y, Shen H.

TNF-α Induced the Enhanced Apoptosis of Mesenchymal Stem Cells in Ankylosing Spondylitis by Overexpressing TRAIL-R2.

Stem Cells Int. 2017;2017:4521324.(IF 3.869)

120. Zhang Y, Wu JY, Weng LH, Li XX, Yu LJ, Xu Y.

Valproic acid protects against MPP+-mediated neurotoxicity in SH-SY5Y Cells through autophagy.

Neurosci Lett. 2017 Jan 18;638:60-68.(IF 2.274)

121. Li L, Sun W, Li L, Liu Y, Wu L, Wang F, Zhou Z, Zhang Z, Huang Y.

A pH-responsive sequential-disassembly nanohybrid for mitochondrial targeting.

Nanoscale. 2017 Jan 7;9(1):314-325.(IF 6.895)

122. Sun W, Li L, Yang QQ, Zhang ZR, Huang Y.

Two birds, one stone: dual targeting of the cancer cell surface and subcellular mitochondria by thegalectin-3-binding peptide G3-C12.

Acta Pharmacol Sin. 2017 Jan 9. doi: 10.1038/aps.2016.137.(IF 5.064)

123. He Z, Pu L, Yuan C, Jia M, Wang J.

Nutrition deficiency promotes apoptosis of cartilage endplate stem cells ina caspase-independent manner partially through upregulating BNIP3.

ACTA BIOCH BIOPH SIN. 2017 Jan;49(1):25-32.(IF 2.836)

124. Yang M, Wang B, Gao J, Zhang Y, Xu W, Tao L.

Spinosad induces programmed cell death involves mitochondrial dysfunction and cytochrome C releasein Spodoptera frugiperda Sf9 cells.

Chemosphere. 2017 Feb;169:155-161.(IF 5.778)

125. Yang YL, Li J, Liu K, Zhang L, Liu Q, Liu B, Qi LW.

Ginsenoside Rg5 increases cardiomyocyte resistance to ischemic injury through regulation of mitochondrial hexokinase-II and dynamin-related protein 1.

Cell Death Dis. 2017 Feb 23;8(2):e2625.(IF 6.304)

126. Li MD, Cheng WP, Shi MX, Ge TD, Zheng XL, Wu DY, Hu XY, Luo JC, Li FL, Li H.

Role of tRNA selenocysteine 1 associated protein 1 in the proliferation and apoptosis of cardiomyocyte like H9c2 cells.

Mol Med Rep. 2017 Feb;15(2):988-994.(IF 2.1)

127. Sun J, Jiang L, Lin Y, Gerhard EM, Jiang X, Li L, Yang J, Gu Z.

Enhanced anticancer efficacy of paclitaxel through multistage tumor-targeting liposomesmodified with RGD and KLA peptides.

INT J NANOMED. 2017 Feb 27;12:1517-1537.(IF 5.115)

128. Yang M, Wang B, Gao J, Zhang Y, Xu W, Tao L.

Spinosad induces programmed cell death involves mitochondrial dysfunction and cytochrome Crelease in Spodoptera frugiperda Sf9 cells.

Chemosphere. 2017 Feb;169:155-161.(IF 5.778)

129. Gao X, Xu H, Shang J, Yuan L, Zhang Y, Wang L, Zhang W, Luan X, Hu G, Chu H, Zhu T, Jia G.

Ozonized carbon black induces mitochondrial dysfunction and DNA damage.

Environ Toxicol. 2017 Mar;32(3):944-955.(IF 3.118)

130. Wu F, Cao W, Xu H, Zhu M, Wang J, Ke X.

Treatment witha selenium-platinum compound induced T-cell acute lymphoblasticleukemia/lymphoma cells apoptosis throughthe mitochondrial signaling pathway.

Oncol Lett. 2017 Mar;13(3):1702-1710.(IF 2.311)

131. Qin Y, Meng L, Fu Y, Quan Z, Ma M, Weng M, Zhang Z, Gao C, Shi X, Han K.

SNORA74B gene silencing inhibits gallbladder cancer cells by inducing PHLPP and suppressingAkt/mTOR signaling.

ONCOTARGET. 2017 Mar 21;8(12):19980-19996.(IF 5.168)

132. Mao XM, Fu QR, Li HL, Zheng YH, Chen SM, Hu XY, Chen QX, Chen QH.

Crocodile choline from Crocodylus siamensis induces apoptosis of human gastric cancer.

TUMOR BIOL . 2017 Mar;39(3):1010428317694320.(IF 3.65)

133. Wei Y, Yu S, Zhang Y, Zhang Y, Zhao H, Xiao Z, Yao L, Chen S, Zhang J.

NDRG2 promotes adriamycin sensitivity through a Bad/p53 complex atthe mitochondria in breast cancer.

ONCOTARGET. 2017 Apr 25;8(17):29038-29047.(IF 5.168)

134. Song C, Luo B, Gong L.

Resveratrol reduces the apoptosis induced by cigarette smoke extract by upregulating MFN2.

PLoS One. 2017 Apr 13;12(4):e0175009.(IF 2.74)

135. Yang J, Zhao JX, Cao Q, Hao L, Zhou D, Gan Z, Ji LN, Mao ZW.

Simultaneously Inducing and Tracking Cancer Cell Metabolism Repression by Mitochondria-Immobilized Rhenium(I) Complex.

ACS APPL MATER INTER. 2017 Apr 26;9(16):13900-13912.(IF 8.758)

136. Lin H, Zhao L, Ma X, Wang BC, Deng XY, Cui M, Chen SF, Shao ZW.

Drp1 mediates compression-induced programmed necrosis of rat nucleus pulposus cells by promoting mitochondrial translocation of p53 and nuclear translocation of AIF.

BIOCHEM BIOPH RES CO. 2017 May 20;487(1):181-188.(IF 2.985)

137. Wu H, Liu S, Gong J, Liu J, Zhang Q, Leng X, Zhang N, Li Y.

VCPA,a novel synthetic derivative ofα-tocopheryl succinate, sensitizes human gastric cancer to doxorubicin-induced apoptosis via ROS-dependent mitochondrial dysfunction.

Cancer Lett. 2017 May 1;393:22-32.(IF 7.36)

138. Chen W, Liu Y, Zhang L, Gu X, Liu G, Shahid M, Gao J, Ali T, Han B.

Nocardia cyriacigeogica from Bovine Mastitis Induced In vitro Apoptosis of Bovine MammaryEpithelial Cells via Activation of Mitochondrial-Caspase Pathway.

FRONT CELL INFECT MI. 2017 May 18;7:194.(IF 4.123)

139. Huang Z, Yang G, Shen T, Wang X, Li H, Ren D.

Dehydrobruceine B enhances the cisplatin-induced cytotoxicity through regulation ofthe mitochondrial apoptotic pathway in lung cancer A549 cells.

Biomed Pharmacother. 2017 May;89:623-631.(IF 4.545)

140. Qi G, Liu Z, Fan R, Yin Z, Mi Y, Ren B, Liu X.

Athyrium multidentatum (Doll.) Ching extract induce apoptosis via mitochondrial dysfunction and oxidative stress in HepG2 cells.

SCI REP-UK. 2017 May 23;7(1):2275.(IF 3.998)

141. Hu X, Kuang Y, Li L, Tang H, Shi Q, Shu X, Zhang Y, Chan FK, Tao Q, He C.

Epigenomic and Functional Characterization of Junctophilin 3 (JPH3) as a Novel Tumor Suppressor Being Frequently Inactivated by Promoter CpG Methylation in Digestive Cancers.

Theranostics. 2017 May 30;7(7):2150-2163.(IF 8.579)

142. Sun W, Li L, Li LJ, Yang QQ, Zhang ZR, Huang Y.

Two birds, one stone: dual targeting ofthe cancer cell surface and subcellular mitochondria by the galectin-3-binding peptide G3-C12.

Acta Pharmacol Sin. 2017 Jun;38(6):806-822.(IF 5.064)

143. Yang DL, Xu JW, Zhu JG, Zhang YL, Xu JB, Sun Q, Cao XN, Zuo WL, Xu RS, Huang JH, Jiang FN, Zhuo YJ, Xiao BQ, Liu YZ, Yuan DB6, Sun ZL, He HC, Lun ZR, Zhong WD, Zhou WL.

Role of GPR30 in estrogen-induced prostate epithelial apoptosis and benign prostatichyperplasia.

BIOCHEM BIOPH RES CO. 2017 Jun 3;487(3):517-524.(IF 2.985)

144. Wang M, Kanako N, Zhang Y, Xiao X, Gao Q, Tetsuya K.

A unique polysaccharide purified from Hericium erinaceus mycelium prevents oxidative stressinduced by H2O2 in human gastric mucosa epithelium cell.

PLoS One. 2017 Jul 24;12(7):e0181546.(IF 2.74)

145. Yang Y, Yang H, Yang J, Li L, Xiang B, Wei Q.

The genetically engineered drug rhCNB induces apoptosis via a mitochondrial route in tumorcells.

ONCOTARGET. 2017 Jul 22;8(39):65876-65888.(IF 5.168)

146. Wang ZB, Zhang S, Li Y, Wang RM, Tong LC, Wang Y, Liu WY, Su DF, Tu Y, Zhang LC, Li L.

LY333531,aPKCβ inhibitor, attenuates glomerular endothelial cell apoptosis inthe early stage of mouse diabetic nephropathy via down-regulating swiprosin-1.

Acta Pharmacol Sin. 2017 Jul;38(7):1009-1023.(IF 5.064)

147. Li Y, Zhang L, Qu T, Tang X, Li L, Zhang G.

Conservation and divergence of mitochondrial apoptosis pathway inthe Pacific oyster, Crassostrea gigas.

Cell Death Dis. 2017 Jul 6;8(7):e2915.(IF 6.304)

148. Hua XW, Bao YW, Chen Z, Wu FG.

Carbon quantum dots with intrinsic mitochondrial targeting ability for mitochondria-basedtheranostics.

Nanoscale. 2017 Aug 3;9(30):10948-10960.(IF 6.895)

149. Li J, Huang Q, Long X, Guo X, Sun X, Jin X, Li Z, Ren T, Yuan P, Huang X, Zhang H, Xing J.

Mitochondrial elongation-mediated glucose metabolism reprogramming is essential for tumourcell survival during energy stress.

Oncogene. 2017 Aug 24;36(34):4901-4912.(IF 7.971)

150. Wang F, Sun W, Li L, Li L, Liu Y, Zhang ZR, Huang Y.

Charge-Reversible Multifunctional HPMA Copolymers for Mitochondrial Targeting.

ACS APPL MATER INTER. 2017 Aug 23;9(33):27563-27574.(IF 8.758)

151. Ying J, Xu J, Shen L, Mao Z, Liang J, Lin S, Yu X, Pan R, Yan C, Li S, Bao Q, Li P.

The Effect of Sodium Fluoride on Cell Apoptosis andthe Mechanism of Human Lung BEAS-2BCells In Vitro.

Biol Trace Elem Res. 2017 Sep;179(1):59-69.(IF 2.639)

152. Wu B, Luo H, Zhou X, Cheng CY, Lin L, Liu BL, Liu K, Li P, Yang H.

Succinate-induced neuronal mitochondrial fission and hexokinase II malfunction in ischemicstroke: Therapeutical effects of kaempferol.

BBA-BIOMEMBRANES. 2017 Sep;1863(9):2307-2318.(IF 3.411)

153. Wang Y, Guo SH, Shang XJ, Yu LS, Zhu JW, Zhao A, Zhou YF, An GH, Zhang Q, Ma B.

Triptolide induces Sertoli cell apoptosis in mice via ROS/JNK-dependent activation ofthe mitochondrial pathway and inhibition of Nrf2-mediated antioxidant response.

Acta Pharmacol Sin. 2017 Sep 14.(IF 5.064)

154. Qie X, Wen D, Guo H, Xu G, Liu S, Shen Q, Liu Y, Zhang W, Cong B, Ma C.

Endoplasmic Reticulum Stress Mediates Methamphetamine-Induced Blood-Brain BarrierDamage.

Front Pharmacol. 2017 Sep 14;8:639.(IF 4.225)

155. Gong L, Tang Y1, 2 An R, Lin M, Chen L, Du J.

RTN1-C mediates cerebral ischemia/reperfusion injury via ER stress and mitochondria-associated apoptosis pathways.

Cell Death Dis. 2017 Oct 5;8(10):e3080.(IF 6.304)

156. Xu F, Ren L, Song M, Shao B, Han Y, Cao Z, Li Y.

Fas-and Mitochondria-Mediated Signaling Pathway Involved in Osteoblast Apoptosis Induced by AlCl3.

Biol Trace Elem Res. 2017 Oct 12.(IF 2.639)

157. Ren T, Zhang H, Wang J, Zhu J, Jin M, Wu Y, Guo X, Ji L, Huang Q, Zhang H, Yang H, Xing J.

MCU-dependent mitochondrial Ca2+ inhibits NAD+/SIRT3/SOD2 pathway to promote ROSproduction and metastasis of HCC cells.

Oncogene. 2017 Oct 19;36(42):5897-5909.(IF 7.971)

158. Cui G, Li Y, Ding K, Hao S, Wang J, Zhang Z.

Attribution of Bax and mitochondrial permeability transition pore on cantharidin-inducedapoptosis of Sf9 cells.

PESTIC BIOCHEM PHYS. 2017 Oct;142:91-101.(IF 2.751)

159. Chen J, Chen B, Zou Z, Li W, Zhang Y, Xie J, Liu C.

Costunolide enhances doxorubicin-induced apoptosis in prostate cancer cells via activatedmitogen-activated protein kinases and generation of reactive oxygen species.

ONCOTARGET. 2017 Nov 21;8(64):107701-107715.(IF 5.168)

160. Lin H, Ma X, Wang BC, Zhao L, Liu JX, Pu FF, Hu YQ, Hu HZ, Shao ZW.

Edaravone ameliorates compression-induced damage in rat nucleus pulposus cells.

Life Sci. 2017 Nov 15;189:76-83.(IF 3.647)

161. Chang G, Liu J, Qin S, Jiang Y, Zhang P, Yu H, Lu K, Zhang N, Cao L, Wang Y, Li Y, Zhang D.

Cardioprotection by exenatide:A novel mechanism via improving mitochondrial functioninvolving the GLP-1 receptor/cAMP/PKA pathway.

Int J Mol Med. 2017 Dec 12.(IF 3.098)

162. Li XM, Zhang XJ, Dong MX.

Isorhynchophylline Attenuates MPP+-Induced Apoptosis Through Endoplasmic Reticulum Stress- and Mitochondria-Dependent Pathways in PC12 Cells: Involvement of Antioxidant Activity.

NEUROMOL MED. 2017 Dec;19(4):480-492.(IF 2.629)

163. Qin Y, Su Z, Wu Y, Wu C, Jin S, Xie W, Jiang W, Zhou R, Cui J.

NLRP11 disrupts MAVS signalosome to inhibit type I interferon signaling and virus-inducedapoptosis.

EMBO Rep. 2017 Dec;18(12):2160-2171.(IF 7.497)

164. Jin X, Zheng X, Li F, Liu B, Li H, Hirayama R, Li P, Liu X, Shen G, Li Q.

Fragmentation level determines mitochondrial damage response and subsequently the fate of cancer cells exposed to carbon ions.

Radiother Oncol. 2017 Dec 2. pii: S0167-8140(17)32736-6.(IF 4.856)

165. Fu K, Wang Y, Guo D, Wang G, Ren H.

Familial Parkinson's Disease-Associated L166P Mutant DJ-1 is Cleaved by Mitochondrial SerineProtease Omi/HtrA2.

Neurosci Bull. 2017 Dec;33(6):685-694.(IF 4.326)

166. Dai G, Zheng D, Guo W, Yang J, Cheng AY

Cinobufagin Induces Apoptosis in Osteosarcoma Cells Via the Mitochondria-Mediated Apoptotic Pathway.

CELL PHYSIOL BIOCHEM. 2018;46(3):1134-1147.(IF 5.5)

167. Gao X, Chen D, Hu X, Zhou Y, Wang Y, Wu C, Chen J, Wang Y, Pei R, Chen X

PLA1A Participates in the Antiviral Innate Immune Response by Facilitating the Recruitment of TANK-Binding Kinase 1 to Mitochondria.

J Innate Immun. 2018;10(4):315-327.(IF 4.932)

168. Zhang J, Li L, Peng Y, Chen Y, Lv X, Li S, Qin X, Yang H, Wu C, Liu Y

Surface chemistry induces mitochondria-mediated apoptosis of breast cancer cells via PTEN/PI3K/AKT signaling pathway.

BBA-MOL CELL RES. 2018 Jan;1865(1):172-185.(IF 4.105)

169. Wang Z, Zhou F, Dou Y, Tian X, Liu C, Li H, Shen H, Chen G.

Melatonin Alleviates Intracerebral Hemorrhage-Induced Secondary Brain Injury in Rats viaSuppressing Apoptosis, Inflammation, Oxidative Stress, DNA Damage, and Mitochondria Injury.

Transl Stroke Res. 2018 Feb;9(1):74-91.(IF 5.78)

170. Wang Y, Guo SH, Shang XJ, Yu LS, Zhu JW, Zhao A, Zhou YF, An GH, Zhang Q, Ma B

Triptolide induces Sertoli cell apoptosis in mice via ROS/JNK-dependent activation of the mitochondrial pathway and inhibition of Nrf2-mediated antioxidant response.

Acta Pharmacol Sin. 2018 Feb;39(2):311-327.(IF 5.064)

171. Wang Z, Zhou F, Dou Y, Tian X, Liu C, Li H, Shen H, Chen G

Melatonin Alleviates Intracerebral Hemorrhage-Induced Secondary Brain Injury in Rats via Suppressing Apoptosis, Inflammation, Oxidative Stress, DNA Damage, and Mitochondria Injury.

Transl Stroke Res. 2018 Feb;9(1):74-91.(IF 5.78)

172. Yuan G, Chen X, Liu Z, Wei W, Shu Q, Abou-Hamdan H, Jiang L, Li X, Chen R, Désaubry L, Zhou F, Xie D

Flavagline analog FL3 induces cell cycle arrest in urothelial carcinoma cell of the bladder by inhibiting the Akt/PHB interaction to activate the GADD45α pathway.

J EXP CLIN CANC RES. 2018 Feb 7;37(1):21.(IF 7.068)

173. Yang X, Tang S, Li D, Li B, Xiao X

ROS-mediated oligomerization of VDAC2 is associated with quinocetone-induced apoptotic cell death.

Toxicol In Vitro. 2018 Mar;47:195-206.(IF 2.959)

174. Chen J, Zhang Y, Li G, Peng F, Jie X, She J, Dongye G, Zou Z, Rong S, Chen L

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J Biol Inorg Chem. 2018 Mar;23(2):261-275.(IF 3.246)

175. Kong J, Wang L, Ren L, Yan Y, Cheng Y, Huang Z, Shen F

Triptolide induces mitochondria-mediated apoptosis of Burkitt's lymphoma cell via deacetylation of GSK-3β by increased SIRT3 expression.

TOXICOL APPL PHARM . 2018 Mar 1;342:1-13.(IF 3.616)

176. Wang R, Deng D, Shao N, Xu Y, Xue L, Peng Y, Liu Y, Zhi F

Evodiamine activates cellular apoptosis through suppressing PI3K/AKT and activating MAPK in glioma.

ONCOTARGETS THER. 2018 Mar 2;11:1183-1192.(IF 3.337)

177. Wang J, Huang Y, Cai J, Ke Q, Xiao J, Huang W, Li H, Qiu Y, Wang Y, Zhang B, Wu H, Zhang Y, Sui X, Bardeesi ASA, Xiang AP.

A Nestin-Cdk5-Drp1 Axis Regulates Neural Stem/Progenitor Cell Stemness via a Metabolic Shift.

Stem Cells. 2018 Apr;36(4):589-601.(IF 6.022)

178. Zhao L, Qi L, Li C, Li L, Jin L, Yuan J

SVCV impairs mitochondria complex Ⅲ resulting in accumulation of hydrogen peroxide.

FISH SHELLFISH IMMUN. 2018 Apr;75:58-65.(IF 3.298)

179. Wang J, Wang C, Bu G

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Exp Ther Med. 2018 Apr;15(4):3650-3658.(IF 1.785)

180. Shen Y, Wu L, Qin D, Xia Y, Zhou Z, Zhang X, Wu X

Carbon black suppresses the osteogenesis of mesenchymal stem cells: the role of mitochondria.

Part Fibre Toxicol. 2018 Apr 12;15(1):16.(IF 7.546)

181. Li Y, Zhang D, Yu K, Hu Y, Wu Q, Qian F, Wang Z

CMPD1 inhibited human gastric cancer cell proliferation by inducing apoptosis and G2/M cell cycle arrest.

Biol Res. 2018 Apr 16;51(1):11.(IF 3.092)

182. Gao XM, Zhu Y, Li JH, Wang XY, Zhang XF, Yi CH, Yang X

microRNA-26a induces a mitochondrial apoptosis mediated by p53 through targeting to inhibit Mcl1 in human hepatocellular carcinoma.

ONCOTARGETS THER. 2018 Apr 19;11:2227-2239.(IF 3.337)

183. Chen D, Yuan X, Liu L, Zhang M, Qu B, Zhen Z, Gao X

Mitochondrial ATAD3A regulates milk biosynthesis and proliferation of mammary epithelial cells from dairy cow via the mTOR pathway.

Cell Biol Int. 2018 May;42(5):533-542.(IF 2.571)

184. Chen XH, Han YT, Ye JL, Chang ZS, Wang CB, Chen SG

Tegillarca granosa extract Haishengsu inhibits tumor activity via a mitochondrial‑mediated apoptotic pathway.

Mol Med Rep. 2018 May;17(5):6828-6834.(IF 2.1)

185. Gong X, Chen Z, Han Q, Chen C, Jing L, Liu Y, Zhao L, Yao X, Sun X

Sanguinarine triggers intrinsic apoptosis to suppress colorectal cancer growth through disassociation between STRAP and MELK.

BMC Cancer. 2018 May 21;18(1):578.(IF 3.15)

186. Shen Y, Wu L, Wang J, Wu X, Zhang X

The Role of Mitochondria in Methamphetamine-induced inhibitory effects on osteogenesis of Mesenchymal Stem Cells.

Eur J Pharmacol. 2018 May 5;826:56-65.(IF 3.263)

187. Yuan Y, Zhang Y, Zhao S, Chen J, Yang J, Wang T, Zou H, Wang Y, Gu J, Liu X, Bian J, Liu Z

Cadmium-induced apoptosis in neuronal cells is mediated by Fas/FasL-mediated mitochondrial apoptotic signaling pathway.

SCI REP-UK. 2018 Jun 11;8(1):8837.(IF 3.998)

188. Jin X, Li F, Liu B, Zheng X, Li H, Ye F, Chen W, Li Q

Different mitochondrial fragmentation after irradiation with X-rays and carbon ions in HeLa cells and its influence on cellular apoptosis.

BIOCHEM BIOPH RES CO. 2018 Jun 12;500(4):958-965.(IF 2.985)

189. Lu YT, Li LZ, Yang YL, Yin X, Liu Q, Zhang L, Liu K, Liu B, Li J, Qi LW

Succinate induces aberrant mitochondrial fission in cardiomyocytes through GPR91 signaling.

Cell Death Dis. 2018 Jun 4;9(6):672.(IF 6.304)

190. Luo J, Qin J, Fu Y, Zhang S, Zhang X, Yang M

6'-Hydroxy Justicidin B Triggers a Critical Imbalance in Ca2+ Homeostasis and Mitochondrion-Dependent Cell Death in Human Leukemia K562 Cells.

Front Pharmacol. 2018 Jun 6;9:601.(IF 4.225)

191. Xu F, Ren L, Song M, Shao B, Han Y, Cao Z, Li Y

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Biol Trace Elem Res. 2018 Jul;184(1):173-185.(IF 2.639)

192. Jia J, Zhang T, Chi J, Liu X, Sun J, Xie Q, Peng S, Li C, Yi L

Neuroprotective Effect of CeO2@PAA-LXW7 Against H2O2-Induced Cytotoxicity in NGF-Differentiated PC12 Cells.

Neurochem Res. 2018 Jul;43(7):1439-1453.(IF 3.038)

193. Qian H, Huang Q, Chen YX, Liu Q, Fang JX, Ye MW

Caspase‑9 was involved in cell apoptosis in human dental pulp stem cells from deciduous teeth.

Mol Med Rep. 2018 Jul;18(1):1067-1073.(IF 2.1)

194. Cheng Y, Jiang Y, Zhang L, Wang J, Chai D, Hu R, Li C, Sun Y, Jiang H

Mesenchymal stromal cells attenuate sevoflurane-induced apoptosis in human neuroglioma H4 cells.

BMC Anesthesiol. 2018 Jul 18;18(1):84.(IF 1.695)

195. Li A, Liu Q, Li Q, Liu B, Yang Y, Zhang N

Berberine Reduces Pyruvate-driven Hepatic Glucose Production by Limiting Mitochondrial Import of Pyruvate through Mitochondrial Pyruvate Carrier 1.

EBioMedicine. 2018 Aug;34:243-255.(IF 5.736)

196. Zhang M, Du H, Huang Z, Zhang P, Yue Y, Wang W, Liu W, Zeng J, Ma J, Chen G, Wang X, Fan J

Thymoquinone induces apoptosis in bladder cancer cell via endoplasmic reticulum stress-dependent mitochondrial pathway.

CHEM-BIOL INTERACT. 2018 Aug 25;292:65-75.(IF 3.723)

197. Qiao C, Ye W, Li S, Wang H, Ding X

Icariin modulates mitochondrial function and apoptosis in high glucose-induced glomerular podocytes through G protein-coupled estrogen receptors.

Mol Cell Endocrinol. 2018 Sep 15;473:146-155.(IF 3.871)

198. Xi Y, Wang W, Wang L, Pan J, Cheng Y, Shen F, Huang Z

Triptolide induces p53-dependent cardiotoxicity through mitochondrial membrane permeabilization in cardiomyocytes.

TOXICOL APPL PHARM . 2018 Sep 15;355:269-285.(IF 3.616)

199. Zhang W, Lu Q, Dong Y, Yue Y, Xiong S

Rv3033, as an Emerging Anti-apoptosis Factor, Facilitates Mycobacteria Survival via Inhibiting Macrophage Intrinsic Apoptosis.

Front Immunol. 2018 Sep 21;9:2136.(IF 5.085)

200. Wang L, Hu Y, Hao Y, Li L, Zheng C, Zhao H, Niu M, Yin Y, Zhang Z, Zhang Y

Tumor-targeting core-shell structured nanoparticles for drug procedural controlled release and cancer sonodynamic combined therapy.

J Control Release. 2018 Sep 28;286:74-84.(IF 7.727)

201. Kong Q, Lv J, Yan S, Chang KJ, Wang G

A Novel Naphthyridine Derivative, 3u, Induces Necroptosis at Low Concentrations and Apoptosis at High Concentrations in Human Melanoma A375 Cells.

Int J Mol Sci. 2018 Sep 29;19(10). pii: E2975.(IF 4.556)

202. Ruan S, Zhang Z, Tian X, Huang D, Liu W, Yang B, Shen M, Tao F

Compound Fuling Granule Suppresses Ovarian Cancer Development and Progression by disrupting mitochondrial function, galactose and fatty acid metabolism.

J Cancer. 2018 Sep 8;9(18):3382-3393.(IF 3.565)

203. Liu Y, Ren L, Liu W, Xiao Z

MiR-21 regulates the apoptosis of keloid fibroblasts by caspase-8 and the mitochondria-mediated apoptotic signaling pathway via targeting FasL.

Biochem Cell Biol. 2018 Oct;96(5):548-555.(IF 2.46)

204. Liu L, Zuo Z, Lu S, Wang L, Liu A, Liu X

Silencing of PINK1 represses cell growth, migration and induces apoptosis of lung cancer cells.

Biomed Pharmacother. 2018 Oct;106:333-341.(IF 4.545)

205. Chang M, Song X, Geng X, Wang X, Wang W, Chen TC, Xie L, Song X

Temozolomide-Perillyl alcohol conjugate impairs Mitophagy flux by inducing lysosomal dysfunction in non-small cell lung Cancer cells and sensitizes them to irradiation.

J EXP CLIN CANC RES. 2018 Oct 16;37(1):250.(IF 7.068)

206. Hong X, Yu Z, Chen Z, Jiang H, Niu Y, Huang Z

High molecular weight fibroblast growth factor 2 induces apoptosis by interacting with complement component 1 Q subcomponent-binding protein in vitro.

J Cell Biochem. 2018 Nov;119(11):8807-8817.(IF 4.237)

207. Lu J, Chen S, Shen M, He Q, Zhang Y, Shi Y, Ding F, Zhang Q

Mitochondrial regulation by pyrroloquinoline quinone prevents rotenone-induced neurotoxicity in Parkinson's disease models.

Neurosci Lett. 2018 Nov 20;687:104-110.(IF 2.274)

208. Liu Y, Li Q, Xiong X, Huang Y, Zhou Z

Mitochondria-targeting and cell-penetrating peptides-co-modified HPMA copolymers for enhancing therapeutic efficacy of α-tocopheryl succinate.

J Mater Chem B. 2018 Dec 146(46):7674-7683. (IF 5.344)

209. Yang ZB, Chen WW, Chen HP, Cai SX, Lin JD, Qiu LZ

MiR-155 aggravated septic liver injury by oxidative stress-mediated ER stress and mitochondrial dysfunction via targeting Nrf-2.

Exp Mol Pathol. 2018 Dec;105(3):387-394.(IF 2.28)

210. Wu N, Zhang X, Du S, Chen D, Che R

Upregulation of miR-335 ameliorates myocardial ischemia reperfusion injury via targeting hypoxia inducible factor 1-alpha subunit inhibitor.

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211. Deng K, Shen J, Wang W, Li M, Li H, Chen C, Zhao H, Zhang M, Xue T, Liu Q, Lui VWY, Hong B, Lin W

Sodium chloride (NaCl) potentiates digoxin-induced anti-tumor activity in small cell lung cancer.

Cancer Biol Ther. 201920(1):52-64.(IF 3.659)

212. Li B, Cao Y, Meng G, Qian L, Xu T, Yan C, Luo O, Wang S, Wei J, Ding Y, Yu D

Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway.

EBioMedicine. 2019 Jan39:239-254.(IF 5.736)

213. Li Z, Li Q, Lv W, Jiang L, Geng C, Yao X, Shi X, Liu Y, Cao J

The interaction of Atg4B and Bcl-2 plays an important role in Cd-induced crosstalk between apoptosis and autophagy through disassociation of Bcl-2-Beclin1 in A549 cells.

FREE RADICAL BIO MED. 2019 Jan130:576-591.(IF 6.17)

214. Zhang W, Wang Y, Wan J, Zhang P, Pei F

COX6B1 relieves hypoxia/reoxygenation injury of neonatal rat cardiomyocytes by regulating mitochondrial function.

Biotechnol Lett. 2019 Jan41(1):59-68.(IF 1.977)

215. Mai CT, Wu MM, Wang CL, Su ZR, Cheng YY, Zhang XJ

Palmatine attenuated dextran sulfate sodium (DSS)-induced colitis via promoting mitophagy-mediated NLRP3 inflammasome inactivation.

Mol Immunol. 2019 Jan105:76-85.(IF 3.641)

216. Tian M, Huang Q, Wang H, Martin FL, Liu L, Zhang J, Shen H

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Reprod Toxicol. 2019 Jan83:54-62.(IF 3.121)

217. Liu W, Yang T, Xu Z, Xu B, Deng Y

Methyl-mercury induces apoptosis through ROS-mediated endoplasmic reticulum stress and mitochondrial apoptosis pathways activation in rat cortical neurons.

FREE RADICAL RES. 2019 Jan53(1):26-44.(IF 2.839)

218. Yu H, Fu QR, Huang ZJ, Lin JY, Chen QX, Wang Q, Shen DY

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Oncol Rep. 2019 Jan41(1):213-223.(IF 3.417)

219. Hao M, Kong C, Jiang C, Hou R, Zhao X, Li J, Wang Y, Gao Y, Zhang H, Yang B, Jiang J

Polydopamine-coated Au-Ag nanoparticle-guided photothermal colorectal cancer therapy through multiple cell death pathways.

Acta Biomater. 2019 Jan 183:414-424.(IF 7.242)

220. Yi Liao, Tariq Hussain, Chunfa Liu, Yongyong Cui, Jie Wang, Jiao Yao, Hehua Chen, Yinjuan Song, Naveed Sabir, Mazhar Hussain, Deming Zhao, Xiangmei Zhou

Endoplasmic Reticulum Stress Induces Macrophages to Produce IL-1β During Mycobacterium bovis Infection via a Positive Feedback Loop Between Mitochondrial Damage and Inflammasome Activation

Front Immunol. 2019 Feb 21;10:268.doi: 10.3389/fimmu.2019.00268.(IF 5.085)

221. Liu Y, Li Q, Xiong X, Zhou Z

Improved mitochondrial targeting effect of HPMA copolymer by SS20 peptide mediation and nonendocytosis pathway.

J Pept Sci. 2019 Feb;25(2):e3144.(IF 1.877)

222. Qiao Z, Cheng Y, Liu S, Ma Z, Li S, Zhang W

Casticin inhibits esophageal cancer cell proliferation and promotes apoptosis by regulating mitochondrial apoptotic and JNK signaling pathways.

N-S ARCH PHARMACOL. 2019 Feb392(2):177-187.(IF 2.05)

223. Zhou XT, Pu ZJ, Liu LX, Li GP, Feng JL, Zhu HC, Wu LF

Inhibition of autophagy enhances adenosine‑induced apoptosis in human hepatoblastoma HepG2 cells.

Oncol Rep. 2019 Feb41(2):829-838.(IF 3.417)

224. Peng K, Xiao J, Yang L, Ye F, Cao J, Sai Y

Mutual Antagonism of PINK1/Parkin and PGC-1α Contributes to Maintenance of Mitochondrial Homeostasis in Rotenone-Induced Neurotoxicity.

Neurotox Res. 2019 Feb35(2):331-343.(IF 2.992)

225. Yang J, Zhu C, Ye J, Lv Y, Wang L, Chen Z, Jiang Z

Protection of Porcine Intestinal-Epithelial Cells from Deoxynivalenol-Induced Damage by Resveratrol via the Nrf2 Signaling Pathway.

J AGR FOOD CHEM. 2019 Feb 1367(6):1726-1735.(IF 4.192)

226. Yuan Y, Yang J, Chen J, Zhao S, Wang T, Zou H, Wang Y, Gu J, Liu X, Bian J, Liu Z

Alpha-lipoic acid protects against cadmium-induced neuronal injury by inhibiting the endoplasmic reticulum stress eIF2α-ATF4 pathway in rat cortical neurons in vitro and in vivo.

Toxicology. 2019 Feb 15414:1-13.(IF 4.099)

227. Liao Y, Hussain T, Liu C, Cui Y, Wang J, Yao J, Chen H, Song Y, Sabir N, Hussain M, Zhao D, Zhou X

Endoplasmic Reticulum Stress Induces Macrophages to Produce IL-1β During Mycobacterium bovis Infection via a Positive Feedback Loop Between Mitochondrial Damage and Inflammasome Activation.

Front Immunol. 2019 Feb 2110:268.(IF 5.085)

228. Li MY, Ding JQ, Tang Q, Hao MM, Wang BH, Wu J, Yu LZ, Jiao M, Luo BH, Xie M, Zhu HL

SIRT1 activation by SRT1720 attenuates bone cancer pain via preventing Drp1-mediated mitochondrial fission.

BBA-MOL BASIS DIS. 2019 Mar 11865(3):587-598.(IF 4.352)

229. Qi W, Zhou L, Zhao T, Ding S, Xu Q, Han X, Zhao Y, Song X, Zhao T, Zhang X, Ye L

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Mol Cell Endocrinol. 2019 Mar 15484:52-58.(IF 3.871)

230. Hu B, Hu S, Yang M, Liao Z, Zhang D, Luo Q, Zhang X, Li H

Growth Hormone Receptor Gene is Essential for Chicken Mitochondrial Function In Vivo and In Vitro.

Int J Mol Sci. 2019 Mar 3120(7). pii: E1608.(IF 4.556)

231. Du S, Li C, Lu Y, Lei X, Zhang Y, Li S, Liu F, Chen Y, Weng D, Chen J

Dioscin Alleviates Crystalline Silica-Induced Pulmonary Inflammation and Fibrosis through Promoting Alveolar Macrophage Autophagy.

Theranostics. 2019 Mar 79(7):1878-1892.(IF 8.579)

232. Song Z, Wang W, Li N, Yan S, Rong K, Lan T, Xia P

Sphingosine kinase 2 promotes lipotoxicity in pancreatic β-cells and the progression of diabetes.

FASEB J. 2019 Mar;33(3):3636-3646.(IF 4.966)

233. Zhang Y, Xi X, Mei Y, Zhao X, Zhou L, Ma M, Liu S, Zha X, Yang Y

High-glucose induces retinal pigment epithelium mitochondrial pathways of apoptosis and inhibits mitophagy by regulating ROS/PINK1/Parkin signal pathway.

Biomed Pharmacother. 2019 Mar111:1315-1325.(IF 4.545)

234. Huang Z, Li Q, Yuan Y, Zhang C, Wu L, Liu X, Cao W, Guo H, Duan S, Xu X, Zhang B, Xing C

Renalase attenuates mitochondrial fission in cisplatin-induced acute kidney injury via modulating sirtuin-3.

Life Sci. 2019 Apr 1222:78-87.(IF 3.647)

235. Xiong W, Ma Z, An D, Liu Z, Cai W, Bai Y, Zhan Q, Lai W, Zeng Q, Ren H, Xu D

Mitofusin 2 Participates in Mitophagy and Mitochondrial Fusion Against Angiotensin II-Induced Cardiomyocyte Injury.

Front Physiol. 2019 Apr 1010:411.(IF 3.367)

236. Ma YC, Zhu YL, Su N, Ke Y, Fan XX, Shi XJ, Liu HM, Wang AF

A novel ent-kaurane diterpenoid analog, DN3, selectively kills human gastric cancer cells via acting directly on mitochondria.

Eur J Pharmacol. 2019 Apr 5848:11-22.(IF 3.263)

237. Chen Y, Ma K

NLRC4 inflammasome activation regulated by TNF-α promotes inflammatory responses in nonalcoholic fatty liver disease.

BIOCHEM BIOPH RES CO. 2019 Apr 9511(3):524-530.(IF 2.985)

238. Fan J, Wu M, Wang J, Ren D, Zhao J, Yang G

1,7-Bis(4-hydroxyphenyl)-1,4-heptadien-3-one induces lung cancer cell apoptosis via the PI3K/Akt and ERK1/2 pathways.

J Cell Physiol. 2019 May234(5):6336-6349.(IF 5.546)

239. Anqi X, Ruiqi C, Yanming R, Chao Y

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J Clin Neurosci. 2019 May63:182-188.(IF 1.76)

240. Zhang L, Lu P, Yan L, Yang L, Wang Y, Chen J, Dai J, Li Y, Kang Z, Bai T, Xi Y, Xu J, Sun G, Yang T

MRPL35 Is Up-Regulated in Colorectal Cancer and Regulates Colorectal Cancer Cell Growth and Apoptosis.

Am J Pathol. 2019 May189(5):1105-1120.(IF 3.491)

241. Chen Y, Chen H, Xie H, Yuan S, Gao C, Yu L, Bi Z

Non‑covalent proteasome inhibitor PI‑1840 induces apoptosis and autophagy in osteosarcoma cells.

Oncol Rep. 2019 May41(5):2803-2817.(IF 3.417)

242. Yang C, Li B, Liu Y, Xing Y

Ginsenoside Rb1 protects cardiomyocytes from oxygen-glucose deprivation injuries by targeting microRNA-21.

Exp Ther Med. 2019 May17(5):3709-3716.(IF 1.785)

243. Ren H, Yang H, Xie M, Wen Y, Liu Q, Li X, Liu J, Xu H, Tang W, Wang M

Chondrocyte apoptosis in rat mandibular condyles induced by dental occlusion due to mitochondrial damage caused by nitric oxide.

Arch Oral Biol. 2019 May101:108-121.(IF 1.931)

244. Zhang J, Bao X, Zhang M, Zhu Z, Zhou L, Chen Q, Zhang Q, Ma B

MitoQ ameliorates testis injury from oxidative attack by repairing mitochondria and promoting the Keap1-Nrf2 pathway.

TOXICOL APPL PHARM . 2019 May 1370:78-92.(IF 3.616)

245. Wang K, Ma H, Liu H, Ye W, Li Z, Cheng L, Zhang L, Lei Y, Shen L, Zhang F

The Glycoprotein and Nucleocapsid Protein of Hantaviruses Manipulate Autophagy Flux to Restrain Host Innate Immune Responses.

Cell Rep. 2019 May 1427(7):2075-2091.e5.(IF 8.109)

246. Gao L, Liu Y, Wang Y, Chen W, Yang K, Li J, Lv B, Zhang X, Chi J, Liu N, Yin X, Zhang X

H2 relaxin ameliorates angiotensin II-induced endothelial dysfunction through inhibition of excessive mitochondrial fission.

BIOCHEM BIOPH RES CO. 2019 May 14512(4):799-805.(IF 2.985)

247. Li R, Wang S, Li T, Wu L, Fang Y, Feng Y, Zhang L, Chen J, Wang X

Salidroside Protects Dopaminergic Neurons by Preserving Complex I Activity via DJ-1/Nrf2-Mediated Antioxidant Pathway.

Parkinsons Dis. 2019 May 162019:6073496.

248. Zhou J, Wang T, Wang H, Jiang Y, Peng S

Obacunone attenuates high glucose-induced oxidative damage in NRK-52E cells by inhibiting the activity of GSK-3β.

BIOCHEM BIOPH RES CO. 2019 May 21513(1):226-233.(IF 2.985)

249. Liu T, Li X, Wu M, Qin L, Chen H, Qian P

Seneca Valley Virus 2C and 3Cpro Induce Apoptosis via Mitochondrion-Mediated Intrinsic Pathway.

Front Microbiol. 2019 May 2910:1202.(IF 4.235)

250. Hu L, Ding M, Tang D, Gao E, Li C, Wang K, Qi B, Qiu J, Zhao H, Chang P, Fu F, Li Y

Targeting mitochondrial dynamics by regulating Mfn2 for therapeutic intervention in diabetic cardiomyopathy.

Theranostics. 2019 May 319(13):3687-3706.(IF 8.579)

251. Sabir N, Hussain T, Liao Y, Wang J, Song Y, Shahid M, Cheng G, Mangi MH, Yao J, Yang L, Zhao D, Zhou X

Kallikrein 12 Regulates Innate Resistance of Murine Macrophages against Mycobacterium bovis Infection by Modulating Autophagy and Apoptosis.

Cells. 2019 May 58(5). pii: E415.(IF 4.366)

252. Peng S, Wang Y, Zhou Y, Ma T, Wang Y, Li J, Huang F, Kou J, Qi L, Liu B, Liu K.

Rare ginsenosides ameliorate lipid overload-induced myocardial insulin resistance via modulating metabolic flexibility.

Phytomedicine. 2019 May58:152745. (IF 4.268)

253. Bao D, Zhao J, Zhou X, Yang Q, Chen Y, Zhu J, Yuan P, Yang J, Qin T, Wan S, Xing J

Mitochondrial fission-induced mtDNA stress promotes tumor-associated macrophage infiltration and HCC progression.

Oncogene. 2019 Jun38(25):5007-5020.(IF 7.971)

254. He W, Liang B, Wang C, Li S, Zhao Y, Huang Q, Liu Z, Yao Z, Wu Q, Liao W, Zhang S, Liu Y, Xiang Y, Liu J, Shi M

MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer.

Oncogene. 2019 Jun38(23):4637-4654.(IF 7.971)

255. Chen J, Wang Y, Du G, Zhang W, Cao T, Shi L, Wang Y, Mi J, Tang G

Down-regulation of miRNA-27b-3p suppresses keratinocytes apoptosis in oral lichen planus.

J Cell Mol Med. 2019 Jun23(6):4326-4337.(IF 4.486)

256. Guo T, Liu T, Sun Y, Liu X, Xiong R, Li H, Li Z, Zhang Z, Tian Z, Tian Y

Sonodynamic therapy inhibits palmitate-induced beta cell dysfunction via PINK1/Parkin-dependent mitophagy.

Cell Death Dis. 2019 Jun 1110(6):457.(IF 6.304)

257. Zhou P, Chen X, Li M, Tan J, Zhang Y, Yuan W, Zhou J, Wang G

2-D08 as a SUMOylation inhibitor induced ROS accumulation mediates apoptosis of acute myeloid leukemia cells possibly through the deSUMOylation of NOX2.

BIOCHEM BIOPH RES CO. 2019 Jun 11513(4):1063-1069.(IF 2.985)

258. Yu S, Zhang L, Liu C, Yang J, Zhang J, Huang L

PACS2 is required for ox-LDL-induced endothelial cell apoptosis by regulating mitochondria-associated ER membrane formation and mitochondrial Ca2+ elevation.

Exp Cell Res. 2019 Jun 15379(2):191-202.(IF 3.383)

259. Zhou LJ, Chen M, Puthiyakunnon S, He C, Xia J, He CY, Deng SQ, Peng HJ

Toxoplasma gondii ROP18 inhibits human glioblastoma cell apoptosis through a mitochondrial pathway by targeting host cell P2X1.

PARASITE VECTOR. 2019 Jun 412(1):284.(IF 2.824)

260. Zhang J, Guo Y, Ge W, Zhou X, Pan M

High glucose induces apoptosis of HUVECs in a mitochondria-dependent manner by suppressing hexokinase 2 expression.

Exp Ther Med. 2019 Jul18(1):621-629.(IF 1.785)

261. Chen P, Hu M, Liu F, Yu H, Chen C

S-allyl-l-cysteine (SAC) protects hepatocytes from alcohol-induced apoptosis.

FEBS Open Bio. 2019 Jul9(7):1327-1336.(IF 2.231)

262. Zhao X, Wu Y, Li J, Li D, Jin Y, Zhu P, Liu Y, Zhuang Y, Yu S, Cao W, Wei H, Wang X, Han Y, Chen G

JNK activation-mediated nuclear SIRT1 protein suppression contributes to silica nanoparticle-induced pulmonary damage via p53 acetylation and cytoplasmic localisation.

Toxicology. 2019 Jul 1423:42-53.(IF 4.099)

263. Zhang H, Hu Y, Wang H, Tian L, Li W, Han L, Xu H, Ma J, Ma K, Xiao B, Chen L

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Am J Transl Res. 2019 Jul 1511(7):4568-4583. eCollection 2019.(IF 3.375)

264. Yuanxin Zhang, Yakun Ge, Wei Shi, Chenming Hu, Xu Bai, Jimin Rong, Ming Yu

CDS-1548 Induces Apoptosis in HeLa Cells by Activating Caspase 3

Oncol Lett. 2019 Aug;18(2):1881-1887.doi: 10.3892/ol.2019.10511.(IF 2.311)

265. Zhang J, Feng J, Ma D, Wang F, Wang Y, Li C, Wang X, Yin X, Zhang M, Dagda RK, Zhang Y

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Mol Neurobiol. 2019 Aug56(8):5586-5607.(IF 4.5)

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Dopamine receptor D1 agonist inhibits glioblastoma via calpain‑mediated ER stress and mitochondrial dysfunction

Oncol Rep. 2021 May;45(5):74.doi: 10.3892/or.2021.8025.(IF 3.417)

352. Xiao-Ling Zhang, Wen-Min Huang, Pei-Chen Tang, Ying Sun, Xin Zhang, Lu Qiu, Bo-Cheng Yu, Xiao-Yan Zhang, Yu-Xin Hong, Yun He, Xiao-Qun Ge

Anti-inflammatory and neuroprotective effects of natural cordycepin in rotenone-induced PD models through inhibiting Drp1-mediated mitochondrial fission

Neurotoxicology. 2021 May;84:1-13.doi: 10.1016/j.neuro.2021.02.002.(IF 3.105)

353. Yilin Zhao, Yaya Wang, Jing Zhao, Zhaohui Zhang, Mingpeng Jin, Feng Zhou, Chao Jin, Jing Zhang, Jinliang Xing, Nan Wang, Xianli He, Tingting Ren

PDE2 Inhibits PKA-Mediated Phosphorylation of TFAM to Promote Mitochondrial Ca2+-Induced Colorectal Cancer Growth

Front Oncol. 2021 Jun 21;11:663778.doi: 10.3389/fonc.2021.663778.(IF 4.848)

354. Qian Chai, Jiajing Miao, Meili Liu, Ziying Zhang, Ziang Meng, Weihua Wu

Knockdown of SGLT1 prevents the apoptosis of cardiomyocytes induced by glucose fluctuation via relieving oxidative stress and mitochondrial dysfunction

Biochem Cell Biol. 2021 Jun;99(3):356-363.doi: 10.1139/bcb-2020-0491.(IF 2.46)

355. Man Zhao, Yuan Wang, Xin Jia, Weina Liu, Xianghong Zhang, Jinfeng Cui

The effect of ochratoxin A on cytotoxicity and glucose metabolism in human esophageal epithelium Het-1A cells

Toxicon. 2021 Jul 30;198:80-92.doi: 10.1016/j.toxicon.2021.05.003.(IF 2.201)

356. Qinglian Wang, Bing Zhao, Jie Zhang, Jingshu Sun, Simeng Wang, Xinyu Zhang, Ying Xu, Rong Wang

Faster lipid β-oxidation rate by acetyl-CoA carboxylase 2 inhibition alleviates high-glucose-induced insulin resistance via SIRT1/PGC-1α in human podocytes

J Biochem Mol Toxicol. 2021 Jul;35(7):e22797.doi: 10.1002/jbt.22797.

357. Ye Li, Xin Wei, Shu-Li Liu, Ying Zhao, Si Jin, Xiao-Yan Yang

Salidroside protects cardiac function in mice with diabetic cardiomyopathy via activation of mitochondrial biogenesis and SIRT3

Phytother Res. 2021 Aug;35(8):4579-4591.doi: 10.1002/ptr.7175.(IF 4.087)

358. Zhihui Yin, Xinyue Geng, Zhengyi Zhang, Ying Wang, Xiaoyan Gao

Rhein Relieves Oxidative Stress in an Aβ1-42 Oligomer-Burdened Neuron Model by Activating the SIRT1/PGC-1α-Regulated Mitochondrial Biogenesis

Front Pharmacol. 2021 Sep 10;12:746711.doi: 10.3389/fphar.2021.746711.(IF 4.225)

359. Jing Sun, Wugui Chen, Songtao Li, Sizhen Yang, Ying Zhang, Xu Hu, Hao Qiu, Jigong Wu, Shangcheng Xu, Tongwei Chu

Nox4 Promotes RANKL-Induced Autophagy and Osteoclastogenesis via Activating ROS/PERK/eIF-2α/ATF4 Pathway

Front Pharmacol. 2021 Sep 28;12:751845.doi: 10.3389/fphar.2021.751845.(IF 4.225)

360. Weihua Wu, Qian Chai, Ziying Zhang

Glucose fluctuation accelerates cardiac injury of diabetic mice via sodium-dependent glucose cotransporter 1 (SGLT1)

Arch Biochem Biophys. 2021 Sep 30;709:108968.doi: 10.1016/j.abb.2021.108968.(IF 3.391)

361. Cai-Ying Hu, Qian-Ying Zhang, Jie-Hui Chen, Bin Wen, Wei-Jian Hang, Kai Xu, Juan Chen, Ben-Hong He

Protective Effect of Salidroside on Mitochondrial Disturbances via Reducing Mitophagy and Preserving Mitochondrial Morphology in OGD-induced Neuronal Injury

Curr Med Sci. 2021 Oct;41(5):936-943.doi: 10.1007/s11596-021-2374-6.(IF 1.273)

362. Songge Deng, Hao Tang, Hanqi Duan, Yizhao Wu, Jiangping Qiu, Yinsheng Li

Mitochondrial bioenergetic, oxidative stress and burrowing responses in earthworm exposed to roxarsone in soil

Ecotoxicol Environ Saf. 2021 Nov 18;228:113003.doi: 10.1016/j.ecoenv.2021.113003.

363. Bing-Xin Chu, Ya-Nan Li, Ning- Liu, Lan-Xin Yuan, Shi-Yan Chen, Yao-Hong Zhu, Jiu-Feng Wang

Salmonella Infantis Delays the Death of Infected Epithelial Cells to Aggravate Bacterial Load by Intermittent Phosphorylation of Akt With SopB

Front Immunol. 2021 Nov 5;12:757909.doi: 10.3389/fimmu.2021.757909.(IF 5.085)

364. Jiexin Zhang, Weijing Feng, Minghui Li, Peier Chen, Xiaodong Ning, Caiwen Ou, Minsheng Chen

Receptor-Interacting Protein Kinase 3 Inhibition Prevents Cadmium-Mediated Macrophage Polarization and Subsequent Atherosclerosis via Maintaining Mitochondrial Homeostasis

Front Cardiovasc Med. 2021 Nov 8;8:737652.doi: 10.3389/fcvm.2021.737652.

365. Dingyi Lv, Minghao Luo, Zhe Cheng, Ruiyu Wang, Xiyang Yang, Yongzheng Guo, Longxiang Huang, Xiang Li, Bi Huang, Jian Shen, Suxin Luo, Jianghong Yan

Tubeimoside I Ameliorates Myocardial Ischemia-Reperfusion Injury through SIRT3-Dependent Regulation of Oxidative Stress and Apoptosis

Oxid Med Cell Longev. 2021 Nov 9;2021:5577019.doi: 10.1155/2021/5577019.(IF 5.076)

366. Ruixian Xing, Xuewen Liu, Buxian Tian, Yan Cheng, Longguang Li

Neuroprotective effect of Na+ /H+ exchangers isoform-1 inactivation against 6-hydroxydopamine-induced mitochondrial dysfunction and neuronal apoptosis in Parkinson's disease models

Drug Dev Res. 2021 Nov;82(7):969-979.doi: 10.1002/ddr.21799.

367. Wenqing Fan, Weifeng Yuan, Xiuyan Ding, Liqian Zhu

β-catenin has potential effects on the expression, subcellular localization, and release of high mobility group box 1 during bovine herpesvirus 1 productive infection in MDBK cell culture

Virulence. 2021 Dec;12(1):1345-1361.doi: 10.1080/21505594.2021.1926409.(IF 5.542)

368. Jiachen Sun, Xinzhu Liu, Chuan'an Shen, Wen Zhang, Yuezeng Niu

Adiponectin receptor agonist AdipoRon blocks skin inflamm-ageing by regulating mitochondrial dynamics

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369. Qianting Luo, Xingyang Li, Wenchao Zhong, Wei Cao, Mingjing Zhu, Antong Wu, Wanyi Chen, Zhitong Ye, Qiao Han, Duraipandy Natarajan, Janak L Pathak, Qingbin Zhang

Dicalcium silicate-induced mitochondrial dysfunction and autophagy-mediated macrophagic inflammation promotes osteogenic differentiation of BMSCs

Regen Biomater. 2021 Dec 13:9:rbab075.doi: 10.1093/rb/rbab075.(IF 4.882)

370. Rongqing Li, Xueqin Li, Jie Zhao, Fandong Meng, Chen Yao, Ensi Bao, Na Sun, Xin Chen, Wanpeng Cheng, Hui Hua, Xiangyang Li, Bo Wang, Hui Wang, Xiucheng Pan, Hongjuan You, Jing Yang, Takayuki Ikezoe

Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation

Theranostics. 2022 Jan 1;12(2):976-998.doi: 10.7150/thno.63751.(IF 8.579)

371. Cheng Jiang, Jiechun Zhang, Huiwen Xie, Huiting Guan, Rui Li, Caixia Chen, Hongzhen Dong, You Zhou, Wei Zhang

Baicalein suppresses lipopolysaccharide-induced acute lung injury by regulating Drp1-dependent mitochondrial fission of macrophages

Biomed Pharmacother. 2022 Jan:145:112408.doi: 10.1016/j.biopha.2021.112408.(IF 4.545)

372. Yujia Li, Hui Chen, Qi Yang, Lixin Wan, Jing Zhao, Yuanyuan Wu, Jiaxin Wang, Yating Yang, Menglan Niu, Hongliang Liu, Junqi Liu, Hushan Yang, Shaogui Wan, Yanming Wang, Dengke Bao

Increased Drp1 promotes autophagy and ESCC progression by mtDNA stress mediated cGAS-STING pathway

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373. Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Acta Pharm Sin B. 2022 Feb;12(2):838-852.doi: 10.1016/j.apsb.2021.07.003.(IF 7.097)

374. Chao Ma, Bixi Gao, Zongqi Wang, Wanchun You, Zhengquan Yu, Haitao Shen, Xiang Li, Haiying Li, Xuwei Zhang, Zhong Wang, Gang Chen

GrpEL1 regulates mitochondrial unfolded protein response after experimental subarachnoid hemorrhage in vivo and in vitro

Brain Res Bull. 2022 Apr:181:97-108.doi: 10.1016/j.brainresbull.2022.01.014.(IF 3.37)

375. Wei Huang, Weidang Xie, Hanhui Zhong, Shumin Cai, Qiaobing Huang, Youtan Liu, Zhenhua Zeng, Yanan Liu

Cytosolic p53 Inhibits Parkin-Mediated Mitophagy and Promotes Acute Liver Injury Induced by Heat Stroke

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376. Rongchuan Yue, Mingming Lv, Meide Lan, Zaiyong Zheng, Xin Tan, Xuemei Zhao, Yulong Zhang, Jun Pu, Lei Xu, Houxiang Hu

Irisin protects cardiomyocytes against hypoxia/reoxygenation injury via attenuating AMPK mediated endoplasmic reticulum stress

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377. Jingjing Lu, Shoupeng Fu, Jie Dai, Jianwen Hu, Shize Li, Hong Ji, Zhiquan Wang, Jiahong Yu, Jiming Bao, Bin Xu, Jingru Guo, Huanmin Yang

Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress

J Zhejiang Univ Sci B. 2022 Jun 15;23(6):461-480.doi: 10.1631/jzus.B2101091.

378. Hui Shi, Ying Yu, Xiaoxiao Liu, Yong Yu, Minghui Li, Yucheng Wang, Yunzeng Zou, Ruizhen Chen, Junbo Ge

Inhibition of calpain reduces cell apoptosis by suppressing mitochondrial fission in acute viral myocarditis

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379. Lei Tian, Ning Li, Kang Li, Yizhe Tan, Jie Han, Bencheng Lin, Wenqing Lai, Huanliang Liu, Yue Shi, Zhuge Xi, Xiaohua Liu

Ambient ozone exposure induces ROS related-mitophagy and pyroptosis via NLRP3 inflammasome activation in rat lung cells

Ecotoxicol Environ Saf. 2022 Jul 15:240:113663.doi: 10.1016/j.ecoenv.2022.113663.

380. Hao Zheng, Senlin Huang, Guoquan Wei, Yili Sun, Chuling Li, Xiaoyun Si, Yijin Chen, Zhenquan Tang, Xinzhong Li, Yanmei Chen, Wangjun Liao, Yulin Liao, Jianping Bin

CircRNA Samd4 induces cardiac repair after myocardial infarction by blocking mitochondria-derived ROS output

Mol Ther. 2022 Nov 2;30(11):3477-3498.doi: 10.1016/j.ymthe.2022.06.016.(IF 8.986)

381. Jing-Yi Zhou, Rui-Rui Yang, Jie Chang, Jia Song, Zi-Sheng Fan, Ying-Hui Zhang, Cheng-Hao Lu, Hua-Liang Jiang, Ming-Yue Zheng, Su-Lin Zhang

Discovery and identification of a novel small molecule BCL-2 inhibitor that binds to the BH4 domain

Acta Pharmacol Sin. 2023 Feb;44(2):475-485.doi: 10.1038/s41401-022-00936-0.(IF 5.064)

382. ZiHao Shen, HuaJun Sheng, Jing Zhao, Jin Xu, ZiLing Cai, Hao Zhang, Zhen Guo, JunNan Liu, Hang Liang, LiHao Tan, ShengWei Gan, Juan Huang, ShuJuan Zhu

AQP8 Modulates Mitochondrial H2O2 Transport to Influence Glioma Proliferation

Cancer Invest. 2024 Apr;42(4):345-356.doi: 10.1080/07357907.2024.2352467.

383. Yajuan Xie, Qian Yuan, Ben Tang, Yaru Xie, Yiling Cao, Yang Qiu, Jieyu Zeng, Zhiwen Wang, Hua Su, Chun Zhang

CPT1A Protects Podocytes From Lipotoxicity and Apoptosis In Vitro and Alleviates Diabetic Nephropathy In Vivo

Diabetes. 2024 Jun 1;73(6):879-895.doi: 10.2337/db23-0811.

384. Zhuoyu Ding, Yiyi Wei, Jingping Dai, Chaomin Pan, Li Yang, Qingyuan Li, Yue Zhang, Qun Yan, Changjie Wu, Aimin Li, Zhixian Lan, Side Liu, Xinke Wang

Deficiency of SDHC promotes metastasis by reprogramming fatty acid metabolism in colorectal cancer

J Transl Med. 2024 Jun 6;22(1):544.doi: 10.1186/s12967-024-05361-x.

385. Xiaobing Lv, Boqin Liu, Xiaoting Su, Xintao Tian, Huating Wang

Unlocking cardioprotection: iPSC exosomes deliver Nec-1 to target PARP1/AIFM1 axis, alleviating HF oxidative stress and mitochondrial dysfunction

J Transl Med. 2024 Jul 26;22(1):681.doi: 10.1186/s12967-024-05204-9.

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