- 询价
- Cell Signaling Technology
- 4155
- USA
- 2025年12月02日
- W
- H,M,R
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- 详细信息
- 技术资料
- 抗体英文名：
EPAC1 (5D3) Mouse mAb
- 抗原：
recombinant fragment of human Epac1
- 应用范围：
W
- 供应商：
CST
- 库存：
大量
- 保质期：
详见说明书
- 适应物种：
H,M,R
- 级别：
详见MSDS文件
- 是否单克隆：
1
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting
Reactivity Key: H=Human M=Mouse R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Isotype |
|---|---|---|---|---|
| W | H M R | Endogenous | 100 | Mouse IgG2a |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | Epac1 (5D3) Mouse mAb detects endogenous levels of total Epac1 protein. |
| Source / Purification | Monoclonal antibody is produced by immunizing animals with a recombinant fragment of human Epac1. Western Blotting
Western blot analysis of extracts from C2C12 cells and whole rat brain using Epac1 (5D3) Mouse mAb. |
| Background | EPAC1 and EPAC2 (exchange proteins activated by cyclic AMP) are guanine nucleotide exchange factors (GEFs) that catalyze the exchange of GDP for GTP, activating Rap1 and Rap2 small GTPases. Rap activation by EPAC is cAMP-dependent and mediates cAMP signaling in part through protein kinase A (PKA) (reviewed in 1). EPAC signaling plays a significant role in a number of cellular processes including migration and focal adhesion formation (2), exocytosis (3), insulin signaling (4), axon growth and guidance (5) and neurotransmitter release (6).
|
| Application References |
Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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