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Syntaxin 6 Antibody

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  • 询价
  • Cell Signaling Technology已认证
  • USA
  • 2025年11月25日
  • W, IP
  • Rabbit
  • H,M,R,Mk
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    • 详细信息
    • 技术资料
    • 抗体英文名

      Syntaxin 6 Antibody

    • 抗原

      synthetic peptide corresponding residue surrounding Tyr140 of mouse syntaxin 6 protein

    • 应用范围

      W, IP

    • 宿主

      Rabbit

    • 级别

      详见MSDS文件

    • 库存

      大量

    • 适应物种

      H,M,R,Mk

    • 保质期

      详见说明书

    • 供应商

      CST

    • 是否单克隆

      2

    • 保存条件

      -20°c

    • 规格

      100 ul (10 western blots)/carrier free & custom formulation / quantity

    规格:产品价格:¥请询价
    规格:100 ul (10 western blots)产品价格:¥请询价
    规格:carrier free & custom formulation / quantity产品价格:¥请询价

    pathway more info application references datasheet PDF MSDS PDF protocols

    Applications Key:  W=Western Blotting  IP=Immunoprecipitation
    Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Monkey
    Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.

    Applications Reactivity Sensitivity MW (kDa) Source
    W IP H M R Mk Endogenous 32 Rabbit
    Protocols
    Specificity / Sensitivity

    Syntaxin 6 Antibody detects endogenous levels of total Syntaxin 6 protein.

    Source / Purification

    Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding residue surrounding Tyr140 of mouse syntaxin 6 protein. Antibodies are purified by protein A and peptide affinity chromatography.

    Western Blotting

    Western Blotting

    Western blot analysis of extracts from various cell lines, using Syntaxin 6 Antibody.

    IP

    IP

    Western blot analysis of A172 lysate (lane1) and immunoprecipitates generated in the absence or presence of A172 cell lysate (lanes 2 and 3), using Syntaxin 6 Antibody both as precipitation and probing antibody.

    Background

    Syntaxin 6 is a ubiquitously expressed S25C family member of the SNARE proteins (1,2). The protein has an amino-terminal H1 domain followed by an H2 SNARE domain and a carboxy-terminal membrane anchor (3). Syntaxin 6 protein is localized to the trans-Golgi and within endosomes and regulates membrane trafficking by partnering with a variety of other SNARE proteins (3-5). Depending on cell type and SNARE parter, syntaxin 6 is involved in the regulation of GLUT4 trafficking, neutrophil exocytosis and granule secretion (6-10).

    1. Bock, J.B. et al. (2001) Nature 409, 839-841.
    2. Bock, J.B. et al. (1996) J. Biol. Chem. 271, 17961-17965.
    3. Wendler, F. and Tooze, S. (2001) Traffic 2, 606-611.
    4. Bock, J.B. et al. (1997) Mol. Biol. Cell 8, 1261-1271.
    5. Mallard, F. et al. (2002) J. Cell Biol. 156, 653-664.
    6. Perera, H.K. et al. (2003) Mol. Biol. Cell 14, 2946-2958.
    7. Shewan, A.M. et al. (2003) Mol. Biol. Cell 14, 973-986.
    8. Mart�n-Mart�n, B. et al. (2000) Blood 96, 2574-25783.
    9. Wendler, F. et al. (2001) Mol. Biol. Cell 12, 1699-1709.
    10. Kuliawat, R. et al. (2004) Mol. Biol. Cell 15, 1690-1701.
    Application References

    Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know !

    Companion Products

    For Research Use Only. Not For Use In Diagnostic Procedures.

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