ERBB3 (2F9) Antibody_ERBB3 (2F9)抗体

ERBB3 (2F9) Antibody_ERBB3 (2F

9)抗体
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  • ¥3000 - 3999
  • Abbiotec已认证
  • 美国
  • 252905
  • 2025年07月14日
  • WB, IF
  • Mouse
  • H
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    • 详细信息
    • 技术资料
    • 免疫原

      Purified recombinant extracellular fragment of human ERBB3 (aa22-369) fused with hIgGFc tag expressed in HEK293 cells.

    • 亚型

      Mouse IgG1

    • 形态

      Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

    • 保存条件

      Store at -20°C

    • 克隆性

      单克隆

    • 标记物

      见下方详细说明

    • 适应物种

      H

    • 保质期

      1-2年

    • 抗原来源

      Purified recombinant extracellular fragment of human ERBB3 (aa22-369) fused with hIgGFc tag expressed in HEK293 cells.

    • 目录编号

      252905

    • 级别

      超纯

    • 库存

      大量

    • 供应商

      Abbiotec

    • 宿主

      Mouse

    • 应用范围

      WB, IF

    • 浓度

      见详细说明信息

    • 靶点

      ERBB3 (2F9)

    • 抗体英文名

      ERBB3 (2F9) Antibody

    • 抗体名

      ERBB3 (2F9) Antibody

    • 规格

      0.1 ml

    ERBB3 (2F9) Antibody_ERBB3 (2F
    ERBB3 (2F9) Antibody产品详细介绍:
    产品名称: ERBB3 (2F9) Antibody
    说明书: 点击查看详细说明及参考图片
    货号: 252905
    规格: 0.1 ml
    产品描述: ERBB3 (v-erb-b2 erythroblastic leukemia viral oncogene homolog 3) is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form.
    克隆类型: Mouse Monoclonal Antibody
    亚型: Mouse IgG1
    免疫原: Purified recombinant extracellular fragment of human ERBB3 (aa22-369) fused with hIgGFc tag expressed in HEK293 cells.
    适用物种: H
    应用范围: WB, IF
    应用说明: WB: 1:500-1:2000; IF: 1:200-1:1000;
    别名: Receptor tyrosine-protein kinase erbB-3; Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3; HER3 ;ERBB3
    形态: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
    保存条件: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
    参考文献:

    ABBIOTEC产品提供质量保证,提供完善的售后和技术支持,ABBIOTEC产品正品包装:
    ERBB3 (2F9) Antibody_ERBB3 (2F ERBB3 (2F9) Antibody_ERBB3 (2F

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