ERBB3 抗体-ERBB3 Antibody

ERBB3 抗体，ERBB3 Antibody，ERBB3 抗体,ERBB3 Antibody

产品名称：ERBB3 抗体-ERBB3 Antibody

产品货号：PSI-13-331-50uL

产品规格：50uL

背景资料：This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized.

保存建议：ERBB3 抗体-ERBB3 AntibodyStore at -20℃

应用类型：WB

点击：ERBB3 抗体-ERBB3 Antibody查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。