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- Sino Biological
- 16053-H02H
- 2025年08月12日
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200 µg
蛋白名称：KIR2DL5蛋白, KIR2DL5 protein
蛋白构建：A DNA sequence encoding the human KIR2DL5A (NP_065396.1) (Met1-His240) was expressed with the Fc region of human IgG1 at the C-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 95 % as determined by SDS-PAGE.
蛋白活性：0
蛋白内毒素：< 1.0 EU per μg protein as determined by the LAL method.
预测N端：His 22
蛋白分子量：The recombinant human KIR2DL5A consists of 457 amino acids and predicts a molecular mass of 50.3 kDa.
蛋白NP号：NP_065396.1
蛋白氨基酸序列：Met1-His240
蛋白标签：C-human IgG1-Fc
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验Binding of Soluble KIR-Fc Fusion Proteins to HLA Class I
Individual natural killer cells express diverse combinations of cell surface receptors, including members of the killer cell immunoglobulin (Ig)-like receptor (KIR) family and of the CD94/NKG2 receptor type. Thus, it is often difficult to assign
HLA 分子参与免疫调节 NK细胞通过直接的细胞毒作用及分泌细胞因子和趋化因子行使功能。NK细胞对靶细胞的杀伤无严格的MHC限制性，而是以“丧失自我”(missingself)的识别方式杀伤缺乏MHC I类抗原或I类抗原发生突变的靶细胞。NK细胞受体主要包括KIR、免疫球蛋白样转录体(1LT)和KLR。其中最受关注的是KIR。按照KIR受体胞内段长短不同分为L型和S型，L型KIR一般含有两个以I／V／L／SxYxxL／V为特征的ITIM，该ITIM在Src家族PTK的作用
The OP9-DL1 System: Generation of T-Lymphocytes from Embryonic or Hematopoietic Stem Cells In Vitro
Problem: The OP9-DL1 cells appear in the FL1 channel. Solution: The OP9-DL1 cells also express green fluorescent protein (GFP) as part of the integrated retroviral bicistronic construct from which both Dll1 and GFP are coexpressed. During flow
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