Tocris货号5665现货IRAK1/4 Inhibito
r I上海睿安生物19121878899安迪Bio-Techne(R&D Systems-Tocris)官方正式授权代理商- ￥11718.01
- Tocris bioscience
- 5665
- made in USA
- 2026年02月27日
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- 详细信息
- 文献和实验
- 技术资料
- 英文名：
IRAK1/4 Inhibitor I
- CAS号：
509093-47-4
- 保质期：
1年
- 保存条件：
−20°C
- 库存：
30⁺瓶
- 供应商：
上海睿安生物19121878899
- 规格：
50mg/瓶
Tocris货号5665-10mg现货IRAK1/4 Inhibitor I上海睿安生物19121878899
安迪Bio-Techne(R&D Systems-Tocris)官方正式授权代理商
Tocris货号5665-50mg现货IRAK1/4 Inhibitor I上海睿安生物19121878899
Chemical Name:N-[1-[2-(4-Morpholinyl)ethyl]-1H-benzimidazol-2-yl]-3-nitroben_zamide
Purity:≥98%
Biological Activity
IRAK1/4 Inhibitor I is an IRAK4 and IRAK1 inhibitor (IC50 values are 0.2 and 0.3 μM, respectively).Technical Data
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
- Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4.
Powers et al.
Bioorg.Med.Chem.Lett., 2006;16:2842 - Bcl10 Regulates Lipopolysaccharide-Induced Pro-Fibrotic Signaling in Bronchial Fibroblasts from Severe Asthma Patients
RK Ramakrishn, K Bajbouj, M Guimei, SS Rawat, Z Kalaji, MY Hachim, B Mahboub, SM Ibrahim, R Hamoudi, R Halwani, Q Hamid
Biomedicines, 2022;10(7):.
Citation for IRAK1/4 Inhibitor I
The citations listed below are publications that use Tocris products. Selected citations for IRAK1/4 Inhibitor I include:
1 Citation: Showing 1 - 1
- SIGIRR Mutation in Human Necrotizing Enterocolitis (NEC) Disrupts STAT3-Dependent microRNA Expression in Neonatal Gut.
Authors: Shahid Et al.
Cell Mol Gastroenterol Hepatol 2021;13:425-440
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文献和实验Tocris货号5665-10mg现货IRAK1/4 Inhibitor I上海睿安生物19121878899
安迪Bio-Techne(R&D Systems-Tocris)官方正式授权代理商
Tocris货号5665-50mg现货IRAK1/4 Inhibitor I上海睿安生物19121878899
Chemical Name:N-[1-[2-(4-Morpholinyl)ethyl]-1H-benzimidazol-2-yl]-3-nitroben_zamide
Purity:≥98%
Biological Activity
IRAK1/4 Inhibitor I is an IRAK4 and IRAK1 inhibitor (IC50 values are 0.2 and 0.3 μM, respectively).Technical Data
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
- Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4.
Powers et al.
Bioorg.Med.Chem.Lett., 2006;16:2842 - Bcl10 Regulates Lipopolysaccharide-Induced Pro-Fibrotic Signaling in Bronchial Fibroblasts from Severe Asthma Patients
RK Ramakrishn, K Bajbouj, M Guimei, SS Rawat, Z Kalaji, MY Hachim, B Mahboub, SM Ibrahim, R Hamoudi, R Halwani, Q Hamid
Biomedicines, 2022;10(7):.
Citation for IRAK1/4 Inhibitor I
The citations listed below are publications that use Tocris products. Selected citations for IRAK1/4 Inhibitor I include:
1 Citation: Showing 1 - 1
- SIGIRR Mutation in Human Necrotizing Enterocolitis (NEC) Disrupts STAT3-Dependent microRNA Expression in Neonatal Gut.
Authors: Shahid Et al.
Cell Mol Gastroenterol Hepatol 2021;13:425-440
Figure 1. DUB assays with Ub‐VS‐untreated 26 proteasome (A , 26S) or Ub‐VS‐treated 26 proteasome (B , VS‐26S) in the USP14 reconstitution system. Ub‐VS is a commercially available active‐site‐directed inhibitor that irreversibly inactivates thiol
Studies of the Ubiquitin Proteasome System
or other proteasome inhibitor (e.g., lactacystin; Calbiochem or Biomol) Phosphate‐buffered saline (PBS; see recipe ) Nondenaturing Triton X‐100 lysis buffer (see recipe ) containing 1×
Nucleic Acid Programmable Protein Arrays: Versatile Tools for Array‐Based Functional Protein Studies
‐88. Ernst, V., Levin, D.H., Foulkes, J.G., and London, I.M. 1982. Effects of skeletal muscle protein phosphatase inhibitor‐2 on protein synthesis and protein
