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文献和实验The hollow fiber assay is a unique in vivo model that allows simultaneous evaluation of up to 6 different cell lines in 2 physiological separate compartments. It was developed by Hollingshead et al. (1) as a preliminary rapid screen
The use of hollow fiber culture is a convenient method for making moderately large quantities of high molecular weight products secreted by human and animal cells at high concentrations and with a higher ratio of product to medium-derived
Construction of a Multicoaxial Hollow Fiber Bioreactor
approaches, and viable-cell design innovation. Herein, we describe the design and construction of a hollow fiber multicoaxial bioreactor with integral oxygenation (i.e., oxygenation within the bioreactor proper) for use with liver cells, but it could be used
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