MOCAc-Lys-Pro-Leu-Gly-Leu-Dap(

Modulation of G Proteins in Rat Striatum by Neuroleptic Drugs and a Peptidomimetic Analog of Pro-Leu-Gly-NH2

Although the dopamine hypothesis of schizophrenia has gained wide acceptance, it has recently become clear that it requires revision (Seeman and Niznik, 1990 ; Ellison, 1994 ; Kahn and Davis, 1995 ). The original hypothesis asserts

切除融合标签常用蛋白酶的酶切位点

Cleavage Sites Table for Fusion Proteins：PROTEASE COMPANY Protease Capture Thrombin Leu-Val-Pro-Arg�Gly-SerAmersham-Biosciences, Novagen, SIGMA, RocheBenzamidine-AgaroseFactor Xa Ile-Glu/Asp-Gly-Arg� Amersham-Biosciences, New England Biolabs

粉状物质（P物质） substance P

1931 年由尤勒（ U.S.von Euler ）和加德姆（ J.H.Gaddum ）发现的肽类，存在于脑及肠管组织中，有降血压和肠管收缩作用。 1971 年从丘脑下部分离出 P 物质的一种，确定了如下结构： Arg-Pro-Lys- Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH 2 。这种物质有使神经元兴奋的强力作用，一般认为与化学递质有密切关系。由于初次单独分离出来的状态是粉状物，故称 P 物质。