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- 文献和实验
- 技术资料
- 器官来源：
肺
- 物种来源：
人
- 是否是肿瘤细胞：
0
- 库存：
大量
- 运输方式：
冻存运输
- 相关疾病：
非小细胞肺癌
- ATCC Number：
CRL-5872™
- 年限：
stage 1
- 生长状态：
贴壁生长
| Designations: | NCI-H1437 [H1437] | ||
| Depositors: | AF Gazdar, JD Minna | ||
| Biosafety Level: | 1 | ||
| Shipped: | frozen | ||
| Medium & Serum: | See Propagation | ||
| Growth Properties: | adherent | ||
| Organism: | Homo sapiens | ||
| Morphology: | |
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| Source: | Organ: lung Tumor Stage: stage 1 Disease: adenocarcinoma; non-small cell lung cancer Derived from metastatic site: pleural effusion |
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| Permits/Forms: | In addition to the MTA mentioned above, other ATCC and/or regulatory permits may be required for the transfer of this ATCC material. Anyone purchasing ATCC material is ultimately responsible for obtaining the permits. Please click here for information regarding the specific requirements for shipment to your location. | ||
| Restrictions: | The line is available with the following restrictions: 1. This cell line was deposited at the ATCC by Dr. A. Gazdar and Dr. J. Minna and is provided for research purposes only. Neither the cell line nor products derived from it may be sold or used for commercial purposes. Nor can the cells be distributed to third parties for purposes of sale, or producing for sale, cells or their products. The cells are provided as service to the research community. They are provided without warranty of merchantability or fitness for a particular purpose or any other warranty, expressed or implied. 2. Any proposed commercial use of the these cells, or their products must first be negotiated with the University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd., Dallas, Texas 75235. Telephone (214) 699-8056, FAX (214) 688-7233. | ||
| Applications: | The line was established in June 1986. | ||
| DNA Profile (STR): | Amelogenin: X CSF1PO: 11,12 D13S317: 12 D16S539: 11,12 D5S818: 11,14 D7S820: 8,11 THO1: 6 TPOX: 9,10 vWA: 18 |
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| Age: | 60 years | ||
| Gender: | male | ||
| Ethnicity: | Caucasian | ||
| Comments: | The line was established in June 1986. The patient was a smoker. 70 pack years. A lymphoblastoid line from the same patient is available as ATCC CRL-5958 . |
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| Propagation: | ATCC complete growth medium: The base medium for this cell line is ATCC-formulated RPMI-1640 Medium, Catalog No. 30-2001. To make the complete growth medium, add the following components to the base medium: fetal bovine serum to a final concentration of 10%. |
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| Preservation: | Culture medium, 95%; DMSO, 5% | ||
| Related Products: | normal (or near-normal) cell line established from the same patient:ATCC CRL-5958 | ||
| References: | 23570: . NCI-Navy Medical Oncology Branch Cell Line Supplement. J. Cell. Biochem. suppl. 24: 1996.. | ||
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文献和实验位于小鼠第 17对染色体（第 1X连锁群）上，是决定小鼠主要组织亲和性抗原 H-2抗原表达的基因。一个小鼠个体的 H-2抗原包括许多抗原的复合体，它至少和 H-2K、 H-2G、 H-2D三个基因座位有关。 H- 2K和 H-2D位于两端，它们之间的交换率为 0.5％。由于在 H-2基因座位内包含有免疫应答基因（ Ir）、补体第四成分基因（ Ss）、雄特有蛋白质基因（ Slp）等，因此 H-2基因又称为 H-2复合体（ H-2 complex）（见图）。此外已经明确在哺乳动物的精子、桑椹
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横纹肌肌原纤维 A带中央稍显明亮的带状部分。 H带的中央有浓的 M线。 H带是 A带中的 A细丝未与 I细丝重叠的部分，肌肉收缩时变窄，松弛时扩展。为亨森（ V． Hensen， 1868）氏所发现，因此而称 H带，即亨森的英文首字。
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