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- 2026年03月01日
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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 品系：
BALB/c
- 物种来源：
小鼠
- 是否是肿瘤细胞：
0
- 细胞类型：
T淋巴细胞
- 生长状态：
悬浮生长
- 相关疾病：
淋巴瘤
- ATCC Number：
TIB-28™
- 细胞形态：
淋巴样
- 运输方式：
冻存运输
- 库存：
大量
| Designations: | S49.1 | ||
| Depositors: | AW Harris | ||
| Biosafety Level: | 1 | ||
| Shipped: | frozen | ||
| Medium & Serum: | See Propagation | ||
| Growth Properties: | suspension | ||
| Organism: | Mus musculus | ||
| Morphology: | lymphoblast |
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| Source: | Disease: lymphoma Strain: BALB/c Cell Type: T lymphocyte; |
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| Permits/Forms: | In addition to the MTA mentioned above, other ATCC and/or regulatory permits may be required for the transfer of this ATCC material. Anyone purchasing ATCC material is ultimately responsible for obtaining the permits. Please click here for information regarding the specific requirements for shipment to your location. | ||
| Antigen Expression: | H-2d; Thy-1.2; TL | ||
| Cytogenetic Analysis: | diploid | ||
| Comments: | The cells are sensitive to 0.001 mM cortisol. 5mcg/ml phytohemagglutinin and 0.01 mM 6-thioguanine. Tested and found negative for ectromelia virus (mousepox). |
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| Propagation: | ATCC complete growth medium: Dulbecco's modified Eagle's medium, 90%; horse serum, 10% |
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| Subculturing: | Medium Renewal: Every 2 to 3 days Cultures can be maintained by addition or replacement of fresh medium. Start cultures at 2 X 10 exp5 cells/ml and maintain between 1 X 10 exp5 and 1 X 10 exp6 cells/ml. |
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| References: | 1104: Ralph P. Retention of lymphocyte characteristics by myelomas and theta+-lymphomas: sensitivity to cortisol and phytohemagglutinin. J. Immunol. 110: 1470-1475, 1973. PubMed: 4541304 1129: Hyman R. Studies on surface antigen variants. Isolation of two complementary variants for Thy 1.2. J. Natl. Cancer Inst. 50: 415-422, 1973. PubMed: 4702114 1130: Ralph P, et al. Independence of theta and TL surface antigens and killing by thymidine, cortisol, phytohemagglutinin, and cyclic AMP in a murine lymphoma. Biochem. Biophys. Res. Commun. 55: 1085-1091, 1973. PubMed: 4358928 1131: Harris AW. Differentiated functions expressed by cultured mouse lymphoma cells. I. Specificity and kinetics of cell responses to corticosteroids. Exp. Cell Res. 60: 341-353, 1970. PubMed: 5422965 22154: Horibata K, Harris AW. Mouse myelomas and lymphomas in culture. Exp. Cell Res. 60: 61-77, 1970. PubMed: 5439579 22177: Bourgeois S, Newby RF. Diploid and haploid states of the glucocorticoid receptor gene of mouse lymphoid cell lines. Cell 11: 423-460, 1977. PubMed: 560913 22241: Schiller JG, et al. Glucocorticoid receptors in lymphoma cells in culture: relationship to glucocorticoid killing activity. Science 171: 189-191, 1971. PubMed: 4395230 22528: Ralph P, Nakoinz I. Inhibitory effects of lectins and lymphocyte mitogens on murine lymphomas and myelomas. J. Natl. Cancer Inst. 51: 883-890, 1973. PubMed: 4542714 |
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文献和实验MECP2的突变可以导致持续性神经系统退化（neurodegenerative disorder）Rett综合症。这个x-染色体相关综合症（X-linked syndrome）主要在女性身上体现，但相对温和的突变也可以导致男性的智力障碍(mental retardation)。 （Figure 1： Pedigrees of the four families (L36, S49, T33, and T
抗体对细胞的毒性剂量 Toxic dose of antibiotics for cell lines
Namalwa 500 1500 Xeno AE3 200 S49 1000 S49 kin- 500
of a prospective multicenter surveillance program [J]. Med Myeol, 2005,43 suppl 1:S49-S58 3. 徐明珠，孙爱宁，吴德沛，，血清半乳甘露聚糖抗原检测对血液病患者侵袭性肺曲霉病的诊断及预后价值，中国抗感染化疗杂志2009年5月20日第9卷第3期 4. 中华内科杂志编辑委员会，血液病/恶性肿瘤患者侵袭性真菌感染的诊断标准与治疗原则(修订版)[J].中华内科杂志，2007,46(7):607-610
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