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Anti-Polo-like kinase-1
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文献和实验Polo-like kinase 1 (Plk1) is a key player in mitosis and has been widely recognized as a therapeutic target for many human cancer types. Apart from its kinase domain, Plk1 harbors a protein–protein interaction domain dubbed “polo-box domain
Polo-Like Kinase-1: Activity Measurement and RNAi-Mediated Knockdown
Polo-like kinase-1 (Plk-1) is an important cell cycle regulatory kinase that has been implicated in a multitude of cell cycle events. In this chapter we review those multiple functions of Plk-1 and describe the methods routinely used
cAMP-dependent protein kinase (PKA) is involved in various cellular functions such as cell proliferation, gene induction, and metabolism (1 ,2 ) and its regulatory subunits have been suggested as a drug target for cancer and other diseases
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