- ¥1880 - 2880
- 百奥莱博
- JN0584-BQC
- 北京
- 2025年07月08日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
415
- 英文名：
Recombinant Human MHC Class I Polypeptide-Related Sequence A
- 保质期：
长期
- 供应商：
北京百奥莱博科技有限公司
- 保存条件：
冻干蛋白置于-20℃
- 规格：
10μg|50μg|500μg|1mg
特别提示：包括重组人MICA在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
产品名称：重组人MICA
英文名称：Recombinant Human MHC Class I Polypeptide-Related Sequence A
产品货号：JN0584
产品规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Glu24-Gln308在C端含有His标签。
MICA质量控制：＞95%(还原性SDS-PAGE)
MICA制剂：冻干品
MICA保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。
MICA复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。
关于MICA：
MHC Class I Polypeptide-Related Sequence A (MICA) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin. MICA shares 85% amino acid identity with a closely related protein, MICB. MICA acts as a stress-induced self-antigen that is recognized by NK cells, NKT cells, and most of the subtypes of T cells. As a Ligand for the KLRK1/NKG2D receptor, MICA binds to KLRK1 leads to cell lysis. MICA functions as an antigen for gamma delta T cells and is frequently expressed in epithelial tumors. MICA antigens are able to elicit the synthesis of alloantibodies in transplant recipients. Studies have shown that anti-MICA antibodies are associated with acute renal allograft rejection and failure. MICA recognition is involved in tumor surveillance, viral infections, and autoimmune diseases.
我公司销售的重组人MICA价格，Recombinant Human MHC Class I Polypeptide-Related Sequence A，重组人MHC Class I Polypeptide-Related Sequence A，重组MHC Class I Polypeptide-Related Sequence A质量上佳，价格普惠，欢迎广大新老客户踊跃订购。
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文献和实验Screening for Antibodies Against MICA by Luminex Flow Cytometry
Antibodies against MICA have been found in organ transplant recipients and were found to be associated with decreased survival of kidney allografts. The MICA antibody screening assay is a Luminex-based solid phase immunoassay designed
High Resolution MICA Genotyping by Sequence-Based Typing (SBT)
We have developed a MICA typing method based on polymerase chain reaction (PCR) sequence-based typing and a computer program that determines the polymorphisms and distinguishes the GCT repeats in exon 5. One PCR amplification was performed
植物源重组人胰岛素生长因子融合蛋白（OsrIGF-1），胰岛素在无血清细胞培养中的最佳替代品。 IGFs家族由两种低分子多肽(IGF-Ⅰ、IGF-Ⅱ)、两类特异性受体及六种结合蛋白组成。IGF-Ⅰ是一个有70个氨基酸的单链碱性蛋白，分子量7649Da，耐热。IGFs的生物学功能不只局限于有丝分裂刺激作用，它们也能诱导分化或促进分化功能的表达。全新推出的植物源重组人类胰岛素生长因子-1融合蛋白（OsrIGF-1）在IGF-1的N末端融合了人血清白蛋白（HSA），HSA作为蛋白质保护剂增加了IGF
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