CD81 单克隆抗体 66866-1-Ig产品图
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CD81 单克隆抗体 66866-1-Ig

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  • ¥1350 - 3000
  • Proteintech已认证
  • 66866-1-Ig
  • 2026年05月21日
  • WB, IHC, IF-P, ELISA
  • Mouse
  • human
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    • 详细信息
    • 询价记录
    • 文献和实验
    • 技术资料
    • 免疫原:

      Recombinant human CD81 protein

    • 亚型:

      IgG1

    • 保存条件:

      Store at -20°C. Stable for one year after shipment.

    • 克隆性:

      Monoclonal

    • 标记物:

      Unconjugated

    • 适应物种:

      human

    • 保质期:

      详见产品包装

    • 库存:

      充足

    • 宿主:

      Mouse

    • 应用范围:

      WB, IHC, IF-P, ELISA

    • 靶点:

      CD81

    • 抗体英文名:

      CD81 Monoclonal antibody

    • 抗体名:

      CD81 Monoclonal antibody

    • 规格:

      50ul/100ul/150ul

    规格:50ul产品价格:¥1350.0
    规格:100ul产品价格:¥2200.0
    规格:150ul产品价格:¥3000.0

    经过测试的应用

    Positive WB detected inRaji cells, HCT 116 cells, HEK-293 cells, Jurkat cells, LPS treated THP-1 cells, Ramos cells, Daudi cells
    Positive IHC detected inhuman tonsillitis tissue
    Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
    Positive IF-P detected inhuman tonsillitis tissue
    Planning an IF experiment? We recommend our CoraLite® Plus 488 conjugated versions of this antibody.

    推荐稀释比

    应用推荐稀释比
    Western Blot (WB)WB : 1:1000-1:6000
    Immunohistochemistry (IHC)IHC : 1:500-1:2000
    Immunofluorescence (IF)-PIF-P : 1:600-1:2400
    It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
    Sample-dependent, Check data in validation data gallery.

    产品信息

    66866-1-Ig targets CD81 in WB, IHC, IF-P, ELISA applications and shows reactivity with human samples.

    经测试应用 WB, IHC, IF-P, ELISA
    文献引用应用WB, IHC, IF
    经测试反应性 human
    文献引用反应性human, pig, rabbit, monkey
    免疫原

    CatNo: Ag27298

    Product name: Recombinant human CD81 protein

    Source: e coli.-derived, PET28a

    Tag: 6*His

    Domain: 114-199 aa of BC002978

    Sequence: VNKDQIAKDVKQFYDQALQQAVVDDDANNAKAVVKTFHETLDCCGSSTLTALTTSVLKNNLCPSGSNIISNLFKEDCHQKIDDLFS

    宿主/亚型 Mouse / IgG1
    抗体类别 Monoclonal
    产品类型 Antibody
    全称 CD81 molecule
    别名 1G2C6, 26 kDa cell surface protein TAPA-1, CD81 antigen, CD81 molecule, S5.7
    计算分子量 26 kDa
    观测分子量 22 kDa
    GenBank蛋白编号BC002978
    基因名称 CD81
    Gene ID (NCBI) 975
    ENSEMBL Gene IDENSG00000110651
    RRIDAB_2882203
    偶联类型 Unconjugated
    形式Liquid
    纯化方式Protein G purification
    UNIPROT IDP60033
    储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
    储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

    背景介绍

    CD81 (also known as TAPA1 or TSPAN28) is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Many of these members are expressed on leukocytes and have been implicated in signal transduction, cell-cell interactions, and cellular activation and development. CD81 is involved in signal transduction and cell adhesion in the immune system (PMID: 9597125). CD81 has also been identified as en essential receptor for HCV (hepatitis C virus) (PMID: 21428934).

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    图标询价记录
    图标暂无询价记录
    图标文献和实验
    该产品被引用文献
    [1]M1 macrophage-derived exosomal miR-20b promotes radiosensitization via CCND1 in HPV+ HNSCC.
    PMID:41395621Front Oncol2025-11-27
    [2]Engineered NK92 cell-derived exosomes inhibit ovarian cancer progression by degrading GPRC5A.
    PMID:41306963Front Immunol2025-11-11
    [3]Tumor-derived exosomal miR-425-5p and miR-135b-3p enhance colorectal cancer progression through immune suppression and vascular permeability promotion.
    PMID:40547161World J Gastrointest Oncol2025-06-15
    [4]Bone Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Ameliorated Lipopolysaccharide-Induced Lung Injury Via the miR-21-5p/PCSK6 Pathway.
    PMID:37937296J Immunol Res2023-10-28
    [5]hASCs-derived exosomal miR-155-5p targeting TGFβR2 promotes autophagy and reduces pyroptosis to alleviate intervertebral disc degeneration.
    PMID:36950198J Orthop Translat2023-03-14
    [6]Keloid Patient Plasma-Derived Exosomal hsa_circ_0020792 Promotes Normal Skin Fibroblasts Proliferation, Migration, and Fibrogenesis via Modulating miR-193a-5p and Activating TGF-β1/Smad2/3 Signaling.
    PMID:36524216Drug Des Devel Ther2022-12-08
    [7]Cancer-associated fibroblast-secreted miR-421 promotes pancreatic cancer by regulating the SIRT3/H3K9Ac/HIF-1α axis.
    PMID:36200682Kaohsiung J Med Sci2022-11
    [8]Malignant Melanoma-Derived Exosomes Induce Endothelial Damage and Glial Activation on a Human BBB Chip Model.
    PMID:35200349Biosensors (Basel)2022-01-31
    [9]lncRNA IGF2-AS Regulates Nucleotide Metabolism by Mediating HMGA1 to Promote Pyroptosis of Endothelial Progenitor Cells in Sepsis Patients.
    PMID:35082972Oxid Med Cell Longev2022-01-17
    [10]Extracellular Vesicles Carry lncRNA SNHG16 to Promote Metastasis of Breast Cancer Cells via the miR-892b/PPAPDC1A Axis.
    PMID:34249903Front Cell Dev Biol2021-06-25
    相关实验
    • CD81分子

      CD81 分子   CD81 常用单克隆抗体或代号: ID6,5A6;(TAPA- 1) 主要表达细胞: 广泛,包括B,T,M [B] 分子质量(kDa)和结构: p26(TM4-SF) 功    能: 增殖抗体靶抗原,与CD19、CD21相连,组成B细胞复合体   CD81 Aka Target of an Anti-Proliferative Antibody (TAPA1)

    • 单克隆抗体制备

      抗体的检测外,还应该用与其抗原成分相关的其它抗原进行交叉试验,方法可用ELISA、IFA法。例如:①制备抗黑色素瘤细胞的McAb,除用黑色素瘤细胞反应外,还应该用其它脏器的肿瘤细胞和正常细胞进行交叉反应,以便挑选肿瘤特异性或肿瘤相关抗原的单克隆抗体。②制备抗重组的细胞因子的单克隆抗体,应首先考虑是否与表达菌株的蛋白有交叉反应,其次是与其它细胞因子间有无交叉。 2.McAb的Ig类与亚类的鉴定   一般在用酶标或荧光素标记的第二抗体进行筛选时已经基本上确定了抗体的Ig类型

    • 免疫球蛋白(immunoglobulim,Ig)

      免疫系统受抗原刺激后,B细胞转化为浆细胞,由浆细胞产生与抗原发生特异性结合的球蛋白,这类球蛋白称为抗体(antibody,Ab)。 免疫球蛋白(immunoglobulim,Ig)是指具有抗体活性或化学结构与抗体相似的球蛋白。 免疫球蛋白普遍存在于哺乳动物和人类的血液、组织液和外分泌中。人体的免疫球蛋白主要有五类:IgM、IgA、IgG、IgD、IgE。 (一) 抗体结构 抗体是具有4条多肽链的对称

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    CD81 单克隆抗体 66866-1-Ig
    ¥1350 - 3000