CD81分子
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CD81 分子
CD81
常用单克隆抗体或代号： ID6,5A6;(TAPA- 1)
主要表达细胞： 广泛,包括B,T,M [B]
分子质量(kDa)和结构： p26(TM4-SF)
功 能： 增殖抗体靶抗原,与CD19、CD21相连,组成B细胞复合体
CD81
Aka Target of an Anti-Proliferative Antibody (TAPA1)
Antibodies against TAPA1 induce homotypic aggregation of cells and can inhibit their growth
Member of CD19/CD21/Leu-13 signal transduction complex; regulates cell growth in unknown manner
May be site of binding of Hepatitis C virus
Positive staining (normal): lymphocytes, endothelial cells, epithelial cells
Negative staining: erythrocytes, platelets, neutrophils
