CYP19A1 多克隆抗体 16554-1-AP
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CYP19A1 多克隆抗体 16554-1-AP

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  • ￥1350 - 3000
  • Proteintech已认证
  • 16554-1-AP
  • 2025年10月13日
  • WB, IHC, IF/ICC, IF-P, ELISA
  • Rabbit
  • human, mouse, rat
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原：

      Recombinant human CYP19A1 protein

    • 亚型：

      IgG

    • 保存条件：

      Store at -20°C. Stable for one year after shipment.

    • 克隆性：

      Polyclonal

    • 标记物：

      Unconjugated

    • 适应物种：

      human, mouse, rat

    • 保质期：

      详见产品包装

    • 库存：

      充足

    • 宿主：

      Rabbit

    • 应用范围：

      WB, IHC, IF/ICC, IF-P, ELISA

    • 靶点：

      CYP19A1

    • 抗体英文名：

      CYP19A1 Polyclonal antibody

    • 抗体名：

      CYP19A1 Polyclonal antibody

    • 规格：

      50ul/100ul/150ul

    规格：50ul产品价格：￥1350.0
    规格：100ul产品价格：￥2200.0
    规格：150ul产品价格：￥3000.0

    经过测试的应用

    Positive WB detected inHEK-293T cells, A2780 cells, human placenta tissue, SKOV-3 cells, mouse liver tissue, mouse ovary tissue, rat ovary tissue
    Positive IHC detected inhuman placenta tissue, rat brain tissue, human kidney tissue, human skeletal muscle tissue, human gliomas tissue, human testis tissue, human spleen tissue, human lung tissue, human ovary tissue
    Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
    Positive IF-P detected inhuman placenta tissue
    Positive IF/ICC detected inHepG2 cells

    推荐稀释比

    应用推荐稀释比
    Western Blot (WB)WB : 1:500-1:2000
    Immunohistochemistry (IHC)IHC : 1:50-1:500
    Immunofluorescence (IF)-PIF-P : 1:50-1:500
    Immunofluorescence (IF)/ICCIF/ICC : 1:200-1:800
    It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
    Sample-dependent, Check data in validation data gallery.

    产品信息

    16554-1-AP targets CYP19A1 in WB, IHC, IF/ICC, IF-P, ELISA applications and shows reactivity with human, mouse, rat samples.

    经测试应用 WB, IHC, IF/ICC, IF-P, ELISA
    文献引用应用WB, IHC, IF
    经测试反应性 human, mouse, rat
    文献引用反应性human, mouse, rat, sheep, goat, geese
    免疫原

    CatNo: Ag9765

    Product name: Recombinant human CYP19A1 protein

    Source: e coli.-derived, PGEX-4T

    Tag: GST

    Domain: 1-181 aa of BC022896

    Sequence: MVLEMLNPIHYNITSIVPEAMPAATMPVLLLTGLFLLVWNYEGTSSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKSSSMFHIMKHNHYSSRFGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRMVTVCAESLKTHLLLFTPASVN
    宿主/亚型 Rabbit / IgG
    抗体类别 Polyclonal
    产品类型 Antibody
    全称 cytochrome P450, family 19, subfamily A, polypeptide 1
    别名 ARO, ARO1, Aromatase, CPV1, CYAR
    计算分子量 20 kDa, 25 kDa, 58 kDa
    观测分子量 49-55 kDa
    GenBank蛋白编号BC022896
    基因名称 CYP19A1
    Gene ID (NCBI) 1588
    RRIDAB_2088670
    偶联类型 Unconjugated
    形式Liquid
    纯化方式Antigen affinity purification
    UNIPROT IDP11511
    储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
    储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

    背景介绍

    CYP19A1(Cytochrome P450 19A1) is also named as ARO1(aromatase), CYAR, CYP19, estrogen synthase and belongs to the cytochrome P450 family. It is a terminal enzyme which transforms irreversibly androgens into estrogens and it is present in the endoplasmic reticulum of numerous tissues(PMID:16406261). The gene encodes a protein with the molecular weight between 46 kDa and 69 kDa(PMID:8129748) and the protein can be glycosylated, but the level of glycosylation does not seem to be essential for CYP19A1 activity(PMID:12606587). Brain aromatase may be neuroprotective by increasing the local estrogen levels in injured neurons so that genetic variation in the brain aromatase gene may modify the risk for AD(PMID:16767510).

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    图标文献和实验
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    humanWB

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    mouseWB

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    rat,mouseWB

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    Authors - Jiansha Li
    • KD Validated
    humanWB,IHC

    Fertil Steril

    Elevated maternal androgen is associated with dysfunctional placenta and lipid disorder in newborns of mothers with polycystic ovary syndrome.

    Authors - Miao Sun
    ratWB

    Environ Pollut

    Hormonal changes and folliculogenesis in female offspring of rats exposed to cadmium during gestation and lactation.

    Authors - Zhiliang Li
    mouseWB

    Endocrinology

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    Authors - Qing He
    图标技术资料

    暂无技术资料 索取技术资料

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    CYP19A1 多克隆抗体 16554-1-AP
    ￥1350 - 3000