- ￥1350 - 3000
- Proteintech
- 14927-1-AP
- 2025年10月13日
- WB, IP, IHC, ELISA
- Rabbit
- human, mouse, rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant human TIMM22 protein
- 亚型：
IgG
- 保存条件：
Store at -20°C. Stable for one year after shipment.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
human, mouse, rat
- 保质期：
详见产品包装
- 库存：
充足
- 宿主：
Rabbit
- 应用范围：
WB, IP, IHC, ELISA
- 靶点：
TIM22
- 抗体英文名：
TIM22 Polyclonal antibody
- 抗体名：
TIM22 Polyclonal antibody
- 规格：
50ul/100ul/150ul
| 规格： | 50ul | 产品价格： | ￥1350.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2200.0 |
| 规格： | 150ul | 产品价格： | ￥3000.0 |
经过测试的应用
| Positive WB detected in | HepG2 cells, MCF-7 cells, mouse liver tissue, rat liver tissue |
| Positive IP detected in | mouse liver tissue |
| Positive IHC detected in | human liver tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:8000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
14927-1-AP targets TIM22 in WB, IHC, IP, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, IP, IHC, ELISA |
| 文献引用应用 | WB |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | human, mouse |
| 免疫原 |
CatNo: Ag6689 Product name: Recombinant human TIMM22 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-194 aa of BC002324 Sequence: MAAAAPNAGGSAPETAGSAEAPLQYSLLLQYLVGDKRQPRLLEPGSLGGIPSPAKSEEQKMIEKAMESCAFKAALACVGGFVLGGAFGVFTAGIDTNVGFDPKDPYRTPTAKEVLKDMGQRGMSYAKNFAIVGAMFSCTECLIESYRGTSDWKNSVISGCITGGAIGFRAGLKAGAIGCGGFAAFSAAIDYYLR |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| 别名 | Testis expressed sequence 4, TEX4, TIM22, TIMM22 |
| 计算分子量 | 20 kDa |
| 观测分子量 | 20 kDa |
| GenBank蛋白编号 | BC002324 |
| 基因名称 | TIM22 |
| Gene ID (NCBI) | 29928 |
| RRID | AB_11183050 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9Y584 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
TIM22 is a translocase localized in mitochondrial inner membrane. It is implicated in import of nuclear-encoded mitochondrial preproteins to the mitochondria. TIM22 is the essential core of protein insertion complex (TIM22 complex) that consists of TIM22, TIM54, TIM18, and TIM12.
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文献和实验| Species | Application | Title |
|---|---|---|
| mouse | WB | Nature The ADP/ATP translocase drives mitophagy independent of nucleotide exchange.Authors - Atsushi Hoshino |
| human | WB | Nat Med The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity.Authors - Wenzhang Wang
|
| human | WB | Cell Stem Cell Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal.Authors - Rashim Pal Singh |
| mouse | WB | Cell Metab Acylglycerol Kinase Maintains Metabolic State and Immune Responses of CD8+ T Cells.Authors - Zhilin Hu |
| human | WB | Cell Metab Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.Authors - Marcel Morgenstern |
| human | WB | Mol Cell Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria.Authors - Milena Vukotic |
Using ProHits to Store, Annotate, and Analyze Affinity Purification–Mass Spectrometry (AP‐MS) Data
coupled with mass spectrometry (AP?MS) is a robust technique used to identify protein?protein interactions. With recent improvements in sample preparation, and dramatic advances in MS instrumentation speed and sensitivity, this technique
： CSB-BP619964 HU >> Baculovirus CSB-MP619964 HU >> Mammalian cell PD1 多克隆抗体 Rabbit anti PD1 货号：CSB-PA619964LA01 HU 识别种属：human，mouse 应用检测：WB、IHC、IF 等 TIM3 重组蛋白 货号：CSB-EP010145 HU TIM3 多克隆抗体
3, Pages 291-298 freecell 另外，这篇文章想必你也看过了。可以追踪一下作者的文章或者引用此文的文献。 Sci. STKE, 22 May 2007 Vol. 2007, Issue 387, p. pe25 Micromanagement During the Innate Immune Response Innate immunity, a well-studied
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