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Collagen Type I 多克隆抗体 14695-1-

AP
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  • ￥1350 - 3000
  • Proteintech已认证
  • 14695-1-AP
  • 2025年10月13日
  • WB, IHC, FC (Intra), IP, ELISA
  • Rabbit
  • human, pig
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    • 详细信息
    • 询价记录
    • 文献和实验
    • 技术资料
    • 免疫原：

      Recombinant human COL1A2 protein

    • 亚型：

      IgG

    • 保存条件：

      Store at -20°C. Stable for one year after shipment.

    • 克隆性：

      Polyclonal

    • 标记物：

      Unconjugated

    • 适应物种：

      human, pig

    • 保质期：

      详见产品包装

    • 库存：

      充足

    • 宿主：

      Rabbit

    • 应用范围：

      WB, IHC, FC (Intra), IP, ELISA

    • 靶点：

      Collagen Type I

    • 抗体英文名：

      Collagen Type I Polyclonal antibody

    • 抗体名：

      Collagen Type I Polyclonal antibody

    • 规格：

      50ul/100ul/150ul

    规格：50ul产品价格：￥1350.0
    规格：100ul产品价格：￥2200.0
    规格：150ul产品价格：￥3000.0

    经过测试的应用

    Positive WB detected inpig skin tissue, human placenta tissue, MG-63 cells, Saos-2 cells, U-87 MG cells
    Positive IP detected inU-87 MG cells
    Positive IHC detected inhuman skin cancer tissue, human colon tissue, human oesophagus cancer tissue, human placenta tissue
    Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
    Positive FC (Intra) detected inSW480 cells

    推荐稀释比

    应用推荐稀释比
    Western Blot (WB)WB : 1:1000-1:4000
    Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
    Immunohistochemistry (IHC)IHC : 1:500-1:2000
    Flow Cytometry (FC) (INTRA)FC (INTRA) : 0.20 ug per 10^6 cells in a 100 µl suspension
    It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
    Sample-dependent, Check data in validation data gallery.

    产品信息

    14695-1-AP targets Collagen Type I in WB, IHC, IF, FC (Intra), IP, CoIP, ELISA applications and shows reactivity with human, pig samples.

    经测试应用 WB, IHC, FC (Intra), IP, ELISA
    文献引用应用WB, IHC, IF, FC (Intra), IP, CoIP
    经测试反应性 human, pig
    文献引用反应性human, mouse, rat, pig, rabbit, canine, chicken, bovine, toad, duck
    免疫原

    CatNo: Ag6281

    Product name: Recombinant human COL1A2 protein

    Source: e coli.-derived, PET28a

    Tag: 6*His

    Domain: 1017-1366 aa of BC054498

    Sequence: RGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDGDFYRADQPRSAPSLRPKDYEVDATLKSLNNQIETLLTPEGSRKNPARTCRDLRLSHPEWSSGYYWIDPNQGCTMDAIKVYCDFSTGETCIRAQPENIPAKNWYRSSKDKKHVWLGETINAGSQFEYNVEGVTSKEMATQLAFMRLLANYASQNITYHCKNSIAYMDEETGNLKKAVILQGSNDVELVAEGNSRFTYTVLVDGCSKKTNEWGKTIIEYKTNKPSRLPFLDIAPLDIGGADQEFFVDIGPVCFK
    宿主/亚型 Rabbit / IgG
    抗体类别 Polyclonal
    产品类型 Antibody
    全称 collagen, type I, alpha 2
    别名 COL1, COL1A2, Alpha-2 type I collagen, col I, Collagen alpha 2(I) chain
    计算分子量 1366 aa, 130 kDa
    观测分子量130-150 kDa
    GenBank蛋白编号BC054498
    基因名称 COL1A2
    Gene ID (NCBI) 1278
    RRIDAB_2082037
    偶联类型 Unconjugated
    形式Liquid
    纯化方式Antigen affinity purification
    UNIPROT IDP08123
    储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
    储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

    背景介绍

    Type I collagen, the major structural component of connective tissues such as skin, tendon and bone, is the most abundant and widely expressed collagen in humans (PMID: 7620364; 8645190; 9016532). Type I collagen is a heterotrimer comprising one alpha 2(I) and two alpha 1(I) chains which are encoded by the unlinked loci COL1A2 and COL1A1 respectively. Type I collagen has a molecular mass of about 250-300 kDa, while the alpha 2(I) chain has a molecular weight of about 100-140 kDa. Mutations in COL1A2 gene are associated with osteogenesis imperfecta, Ehlers-Danlos syndrome, idiopathic osteoporosis, and atypical Marfan syndrome. This antibody raised against 1017-1366 aa of human pro-alpha 2 chain of type l collagen can recognize collagen alpha 2(1) chain and C-terminal propeptide of pro-alpha 2(1) chain.

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    Collagen Type I 多克隆抗体 14695-1-AP
    ￥1350 - 3000