- ￥1350 - 3000
- Proteintech
- 10216-1-AP
- 2025年10月13日
- WB, IHC, ELISA
- Rabbit
- human, mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant human RARRES2 protein
- 亚型：
IgG
- 保存条件：
Store at -20°C. Stable for one year after shipment.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
human, mouse
- 保质期：
详见产品包装
- 库存：
充足
- 宿主：
Rabbit
- 应用范围：
WB, IHC, ELISA
- 靶点：
Chemerin/RARRES2
- 抗体英文名：
Chemerin/RARRES2 Polyclonal antibody
- 抗体名：
Chemerin/RARRES2 Polyclonal antibody
- 规格：
50ul/100ul/150ul
| 规格： | 50ul | 产品价格： | ￥1350.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2200.0 |
| 规格： | 150ul | 产品价格： | ￥3000.0 |
经过测试的应用
| Positive WB detected in | human plasma tissue |
| Positive IHC detected in | human placenta tissue, mouse liver tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Chemerin has low expression in most cells and tissues
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:200-1:1000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
10216-1-AP targets Chemerin/RARRES2 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, IHC, ELISA |
| 文献引用应用 | WB, IHC, IF |
| 经测试反应性 | human, mouse |
| 文献引用反应性 | human, mouse |
| 免疫原 |
CatNo: Ag0261 Product name: Recombinant human RARRES2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-163 aa of BC000069 Sequence: MRRLLIPLALWLGAVGVGVAELTEAQRRGLQVALEEFHKHPPVQWAFQETSVESAVDTPFPAGIFVRLEFKLQQTSCRKRDWKKPECKVRPNGRKRKCLACIKLGSEDKVLGRLVHCPIETQVLREAEEHQETQCLRVQRAGEDPHSFYFPGQFAFSKALPRS |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | retinoic acid receptor responder (tazarotene induced) 2 |
| 别名 | RARRES2, Tazarotene-induced gene 2 protein, RAR-responsive protein TIG2, RAR responsive protein TIG2, HP10433 |
| 计算分子量 | 163 aa, 19 kDa |
| 观测分子量 | 14-19 kDa |
| GenBank蛋白编号 | BC000069 |
| 基因名称 | RARRES2 |
| Gene ID (NCBI) | 5919 |
| RRID | AB_2269231 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q99969 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Chemerin, also named as TIG2 and RARRES2, is adipocyte-secreted protein (adipokine) that regulates adipogenesis, metabolism and inflammation through activation of the chemokine-like receptor 1 (CMKLR1). Its other ligands include G protein-coupled receptor 1 (GPR1) and chemokine receptor-like 2 (CCRL2). It positively regulates adipocyte differentiation, modulates the expression of adipocyte genes involved in lipid and glucose metabolism and might play a role in angiogenesis, a process essential for the expansion of white adipose tissue. RARRES2 have both pro- and anti-inflammatory properties depending on the modality of enzymatic cleavage by different classes of proteases. The MW of Chemerin is 14-19 kDa.
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文献和实验| Species | Application | Title |
|---|---|---|
| mouse,human | IHC,WB | Mil Med Res RARRES2 regulates lipid metabolic reprogramming to mediate the development of brain metastasis in triple negative breast cancerAuthors - Yi-Qun Li |
| human | WB | Cancer Cell Int Targeting copper death genotyping associated gene RARRES2 suppresses glioblastoma progression and macrophages infiltrationAuthors - Tao Yan |
| human,mouse | WB,IHC | Front Pharmacol Targeting the chemerin/CMKLR1 axis by small molecule antagonist α-NETA mitigates endometriosis progressionAuthors - Ming Yu
|
| human | IHC | Front Oncol Neutrophils Promote Tumor Progression in Oral Squamous Cell Carcinoma by Regulating EMT and JAK2/STAT3 Signaling Through Chemerin.Authors - Xiaoyuan Hu |
| human | WB | J Zhejiang Univ Sci B Silencing of DsbA-L gene impairs the PPARγ agonist function of improving insulin resistance in a high-glucose cell model.Authors - Xuan Zhou |
| mouse | IF | Mol Med Assessing personalized molecular portraits underlying endothelial-to-mesenchymal transition within pulmonary arterial hypertensionAuthors - Ruhao Wu |
因此，综合来说，EarthOx的GST标签抗体 （货号#E022040）是一款同时具有高特异性、高灵敏度、多应用类型以及性价比的GST标签抗体。同时，我们也提供其他品牌的GST标签抗体，如Proteintech的GST多克隆抗体 ――GST PolyClonal Antibody（货号#10000-0-AP）以及Abcam、Santa等多种GST标签抗体产品。更多GST标签抗体以及其他如His、HA、Myc、GFP、Flag等其他标签抗体，请电话垂询。美国EarthOx品牌是一家提供高性价比免疫学和细胞
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