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- 英文名：
Shanghai Model Organisms Center, Inc.
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上海南方模式生物科技股份有限公司
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文献和实验3 and disproportionate micromelia (Dmm ) to α1 type II collagen (Col2a1 ) locus on chromosome 15. We have identified the mutation in cho , which is a deletion of a cytosine residue in the coding region of Col11a1 mRNA (1 ). In Dmm , a deletion of three nucleotides
Analysis of Arthritic Lesions in the Del1 Mouse: A Model for Osteoarthritis
of Col2a1 transgenes with a short deletion mutation results in production of shortened proα1(II) collagen chains and a phenotype resembling human OA. This chapter describes techniques and practical aspects of preparation and processing of skeletal samples
Human Chondrocyte Cultures as Models of Cartilage-Specific Gene Regulation
The mature articular chondrocyte embedded in the cartilage matrix is a resting cell with no detectable mitotic activity and a very low synthetic activity (1 ). The markers of mature articular chondrocytes are type II collagen (COL2A1
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