Mouse Anti Human CD40 Biotinylated
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Mouse Anti Human CD40 Biotinyl

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  • ¥4830 - 7100
  • Prospecbio
  • 以色列
  • ant-264
  • 2025年07月12日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      for future use below -18°C

    • 保质期

      See instructions

    • 英文名

      CD40 Biotin

    • 库存

      常规产品有备货

    • 供应商

      上海经科化学科技有限公司

    • CAS号

    • 规格

      0.5mg/1mg

    规格:0.5mg产品价格:¥4830.0
    规格:1mg产品价格:¥7100.0

    Mouse Anti Human CD40 Biotinyl

    CATALOGUE NUMBER

    ANT-264

    SYNONYMS

    p50, Bp50, CDW40, MGC9013, TNFRSF5, CD40.

    TYPE

    Mouse Anti Human Monoclonal.

    INTRODUCTION

    CD40 is part of the TNF-receptor superfamily. CD40 is a necessary mediator for vast range of immune and inflammatory responses together with T cell-dependent immunoglobulin class switching, memory B cell growth, and germinal center formation. The transcription factor AKNA regulates the expression of CD40 and its ligand, which is vital for homotypic cell interactions. Adaptor protein TNFR2 interacts with CD40 and serves as a mediator of the signal transduction. The interaction of CD40 and its ligand is crucial for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is the receptor for TNFSF5/CD40L.

    CLONE

    hCD40.

    IMMUNOGEN

    Activated Human B cells.

    IG SUBCLASS

    Mouse IgG1.

    PURIFICATION METHOD

    Protein-A.

    FORMULATION

    1mg/ml in PBS (after reconstitution).

    STORAGE PROCEDURES

    Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

    SOLUBILITY

    Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

    APPLICATIONS

    Staining antibody. For staining, use 10µl/1,000,000 cells.

    AVAILABLE CONJUGATES

    This antibody is also available unconjugated and conjugated to FITC. For staining with biotin or FITC-conjugated antibody use 5-10µl/106 cells.

    SAFETY DATA SHEET

    SDS

    USAGE

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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    图标文献和实验
    该产品被引用文献

    CD40 is part of the TNF-receptor superfamily. CD40 is a necessary mediator for vast range of immune and inflammatory responses together with T cell-dependent immunoglobulin class switching, memory B cell growth, and germinal center formation. The transcription factor AKNA regulates the expression of CD40 and its ligand, which is vital for homotypic cell interactions. Adaptor protein TNFR2 interacts with CD40 and serves as a mediator of the signal transduction. The interaction of CD40 and its ligand is crucial for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is the receptor for TNFSF5/CD40L.

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    文献支持
    Mouse Anti Human CD40 Biotinylated
    ¥4830 - 7100