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- 文献和实验
- 技术资料
- 保存条件:
for future use below -18°C
- 保质期:
See instructions
- 英文名:
mProlactin, His
- 库存:
部分小规格有备货
- 供应商:
上海经科化学科技有限公司
- CAS号:
无
- 规格:
1ug/5ug/50ug
| 规格: | 1ug | 产品价格: | ¥1080.0 |
|---|---|---|---|
| 规格: | 5ug | 产品价格: | ¥2415.0 |
| 规格: | 50ug | 产品价格: | ¥20286.0 |

CATALOGUE NUMBER
CYT-1060
SYNONYMS
AV290867, Gha1, Prl1a1, Growth hormone a1, Mammotropin, Luterotropic hormone, Lutetropin, PRL.
INTRODUCTION
Prolactin is a neuroendocrine hormone synthesized primarily by the pituitary gland but also a variety of other cell types including the placenta, brain and uterus. Its primary function is to promote and maintain lactation but has also been shown to have a role in breast cancer development, regulation of reproductive function and immunoregulation.
DESCRIPTION
Prolactin Mouse produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 222 amino acids (30-228a.a.) and having a molecular mass of 25 kDa.
Prolactin Mouse protein is fused to a 23 amino acid His tag at N-terminus and is purified by standard chromatography.
SOURCE
PHYSICAL APPEARANCE
FORMULATION
The Prolactin Mouse solution (0.25mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 20% glycerol.
STABILITY
Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
AMINO ACID SEQUENCE
Mg-s-sHHHHHH SSGLVPRGSH MGSQPLPICS AGDCQTSLRE LFDRVVILSH YIHTLYTDMF IEFDKQYVQD REFMVKVIND CPTSSLATPE DKEQALKVPP EVLLNLILSL VQSSSDPLFQ LITGVGGIQE APEYILSRAK EIEEQNKQLL EGVEKIISQA YPEAKGNGIY VWSQLPSLQ GVDEESKILS LRNTIRCLRR DSHKVDNFLK VLRCQIAHQN NC.
PURITY
SAFETY DATA SHEET
SDS
USAGE
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文献和实验Prolactin is a neuroendocrine hormone synthesized primarily by the pituitary gland but also a variety of other cell types including the placenta, brain and uterus. Its primary function is to promote and maintain lactation but has also been shown to have a role in breast cancer development, regulation of reproductive function and immunoregulation.
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从罕见病到“不限癌种”,NRG1靶点凭什么一年内连斩三大适应症?
的NRG1都含有α、β两种EGF样结构域。EGF样受体结合域是ERBB受体酪氨酸激酶活化的必要条件,位于胞外结构域的近膜区 [6]。 图1. NRG1蛋白结构示意图 *本图来源于Prolactin 出版物[6]。 NRG1主要表达于胶质细胞和神经元以及乳腺、心肌、肺、肾、肝等器官,在神经系统、心肌、乳腺发育中起重要作用 [4, 5]。有研究发现,NRG1β在神经系统、心肌细胞内表达较NRG1α高,而NRG1α在乳腺中的表达较NRG1β高 [7, 8]。此外,越来越多的研究表明NRG1融合与多种肿瘤
Studies of the Ubiquitin Proteasome System
with Nonradioactive Tag (Biotin) Alternate Protocol 10: Generation of Tagged Ubiquitin Expression Plasmids Basic Protocol 18: Immunoblotting with Anti‐Ubiquitin Generation and Purification of Rabbit Anti‐Ubiquitin Antibodies Basic Protocol 19: Generation
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