Product overview
Description Anti-PIK3CG rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human PIK3CG
Reactivity Human, Mouse
Content 0.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-PIK3CG antibody Target information
Symbol PIK3CG
Full name phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Synonyms PI3K; PIK3; PI3CG; PI3Kgamma; p110gamma; p120-PI3K
Swissprot P48736
Target Background
This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells.