Anti-PIK3CG antibody

Anti-PIK3CG antibody

Cat. No.     JLC162051
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-PIK3CG rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human PIK3CG
Reactivity                 Human, Mouse
Content                     0.5 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 PIK3CG
Full name                 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Synonyms    PI3K; PIK3; PI3CG; PI3Kgamma; p110gamma; p120-PI3K
Swissprot    P48736

Target Background
This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells.