Anti-ITGA4 antibody

Anti-ITGA4 antibody

Cat. No.     JC120890        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-ITGA4 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human ITGA4
Reactivity                 Human, Mouse
Content                     0.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-ITGA4 antibody
Target information
Symbol                 ITGA4
Full name                 integrin subunit alpha 4
Synonyms    IA4; CD49D
Swissprot    P13612

Target Background
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.

Anti-ITGA4 antibody
Applications
Immunohistochemistry
Predicted cell location: Cell membrane
Positive control: Human thyroid cancer
Recommended dilution: 20-100