Anti-H3F3B antibody

Anti-H3F3B antibody

Cat. No.   JC125570        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-H3F3B rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human H3F3B
Reactivity                 Human, Mouse, Rat
Content                     0.72 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-H3F3B antibody
Target information
Symbol                 H3F3B
Full name                 H3 histone family member 3B
Synonyms    H3.3B
Swissprot    P84243

Target Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded by this gene is a replication-independent histone that is a member of the histone H3 family. Pseudogenes of this gene have been identified on the X chromosome, and on chromosomes 5, 13 and 17.

Anti-H3F3B antibody
Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human thyroid cancer
Recommended dilution: 30-150    Predicted cell location: Nucleus
Positive control: Human cervical cancer
Recommended dilution: 30-150