- 询价
- gelatins
- JC263494
- 进口/国产
- 2025年07月15日
- ELISA, WB
- Rabbit
- 人/动物/植物
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- 详细信息
- 技术资料
- 供应商：
上海机纯实业有限公司
- 库存：
大量
- 克隆性：
单克隆
- 保质期：
12个月
- 抗体英文名：
Anti-CARD16 antibody
- 宿主：
Rabbit
- 适应物种：
人/动物/植物
- 应用范围：
ELISA, WB
- 浓度：
0.6 mg/ml
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Anti-CARD16 antibody
Cat. No. JC263494
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-CARD16 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Synthetic peptide of human CARD16
Reactivity Human
Content 0.6 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CARD16
Full name caspase recruitment domain family member 16
Synonyms COP; COP1; PSEUDO-ICE
Swissprot Q5EG05
Target Background
Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
Anti-CARD16 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 25-100 Predicted cell location: Cytoplasm
Positive control: Human ovarian cancer
Recommended dilution: 25-100
Cat. No. JC263494
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-CARD16 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Synthetic peptide of human CARD16
Reactivity Human
Content 0.6 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CARD16
Full name caspase recruitment domain family member 16
Synonyms COP; COP1; PSEUDO-ICE
Swissprot Q5EG05
Target Background
Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
Anti-CARD16 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 25-100 Predicted cell location: Cytoplasm
Positive control: Human ovarian cancer
Recommended dilution: 25-100
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Anti-CARD16 antibody
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