CD134(OX40) MicroBeads,rat

Pristane-Induced Arthritis in the Rat

A chronic relapsing arthritis develops after a single subcutaneous injection of small amounts of pristane; the pristane induced arthritis (PIA) model in the rat. PIA is characterized by a sudden onset of disease 2 wk after induction. The main

Convenient and Efficient Enrichment of the CD133+ Liver Cells from Rat Fetal Liver as a Source of Liver Stem/Progenitor Cells

(LSPCs). Here, we describe a convenient and efficient method (three-step method) to enrich LSPCs. The fetal liver cells (FLCs) were firstly enriched by Percoll discontinuous gradient centrifugation from the rat fetal liver. Then the FLCs in culture

「少吃」真的可以帮助杀死癌细胞！模拟禁食可重塑机体免疫，提高癌症免疫治疗的效果

为了确定免疫系统在其中的作用，他们在 NSG 免疫缺陷乳腺癌小鼠中使用了相同的治疗方案。禁食模拟饮食联合抗 OX40/抗 PD-L1 治疗在免疫缺陷小鼠中已不再有效，提示 FMD 联合抗 OX40/抗 PD-L1 治疗的抗肿瘤作用是由免疫系统介导的。 图片来源：Cell Reports 禁食模拟饮食联合抗 OX40/抗 PD-L1 治疗通过促进 T 细胞活化来增强抗肿瘤反应 为了探讨禁食模拟饮食如何提高抗肿瘤活性，他们从乳腺癌小鼠模型中分离出 CD45 阳性肿瘤浸润性免疫细胞，并进