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文献和实验Naturally occurring CD4+ CD25+ T regulatory cells originate from the thymus and play a central role regarding the maintenance of peripheral tolerance by suppression of autoreactive T-cell populations. However, T regulatory cells
Polyclonal Expansion of Human CD4+CD25+ Regulatory T Cells
Based on results from experimental animal models, the adoptive transfer of CD4+ CD25+ FOXP3+ regulatory T cells (Treg) is expected to be efficacious in treating autoimmune and inflammatory diseases, as well as in preventing alloresponses
Isolation, Flow Cytometric Analysis, and Suppression Assay of CD4+ CD25+ T-Regulatory Cells
-allergic) individuals do not. Recently, attention has focused on regulatory mechanisms, such as T-regulatory cells, preventing IgE responses to allergens in nonatopic individuals. Regulatory CD4+CD25+ T cells have been described in both mice and humans
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