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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 保质期:
12个月
- 英文名:
Recombinant Human High affinity immunoglobulin epsilon receptor subunit gamma (FCER1G), partial
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
10ug/20ug/50ug/100ug/200ug/500ug/1mg
| 规格: | 10ug | 产品价格: | ¥69.0 |
|---|---|---|---|
| 规格: | 20ug | 产品价格: | ¥139.0 |
| 规格: | 50ug | 产品价格: | ¥209.0 |
| 规格: | 100ug | 产品价格: | ¥349.0 |
| 规格: | 200ug | 产品价格: | ¥419.0 |
| 规格: | 500ug | 产品价格: | ¥559.0 |
| 规格: | 1mg | 产品价格: | ¥699.0 |
Research Areas
ImmunologyUniprot ID
P30273Gene Names
FCER1GAlternative Name(s)
Fc receptor gamma-chain ;FcRgammaFc-epsilon RI-gammaIgE Fc receptor subunit gamma ;FceRI gammaLead Time
3-7 business daysOrganism
Homo sapiens (Human)Source
E.coliExpression Region
45-86aaProtein Length
Cytoplasmic DomainTag Info
N-terminal 6xHis-B2M-taggedTarget Protein Sequence
RLKIQVRKAAITSYEKSDGVYTGLSTRNQETYETLKHEKPPQMW
18.9 kDaPurity
Greater than 90% as determined by SDS-PAGE.Form
Lyophilized powder.If the size you ordered does not have lyophilized powder in stock, we will provide it in liquid formBuffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Micropatterned Ligand Arrays to Study Spatial Regulation in Fc Receptor Signaling
Fc receptor signaling plays a fundamental role in immune responses. A plethora of Fc �receptors (e.g., Fc gamma, Fc-alpha, and Fc-epsilon) are expressed on different immune cells, including natural killer cells, macrophages, mast cells
,亲合力增高Kd为10-8M。IgG与Clq结合点位于CH2功能区中最后一个β折叠股318~322位氨基酸残基(Glu-x-Lys-x-Lys)。IgM倍以上。人类天然的抗A和抗B血型抗体为IgM,血型不符合引韦的输血反应发生快而且严重。 2.凝聚的IgA、IgG4和IgE等可通过替代途径活化补体。 (三)结合Fc受体 不同细胞表面具有不同Ig的Fc受体,分别用FcγR、FcεR、FcαR等来表示。当Ig与相应抗原
免疫球蛋白的H链和L链均由V区和C区组成,每条链都有110个氨基酸组成的结构域(domain)的重复。每个结构域内每隔60个氨基酸有两个链内的二硫键连接。L链有一个可变结构域(V1)和一个恒定结构域(CL);H链则有一个可变结构域(VH)和3个(α、γ、δ链)或4个(μ、ε链)恒定结构域(CHI、CH2、CH3、CH4)。IgG经木瓜蛋白酶短暂作用后,可获得两个片段,相对分子质量分别为4.5x104和5.0x106,前者具有抗原结合
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