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- 文献和实验
- 技术资料
- 免疫原:
Recombinant Human Tetraspanin-12 protein (111-224AA)
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
HRP
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
O95859
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA
- 浓度:
>95%,Protein G purified
- 靶点:
TSPAN12
- 抗体英文名:
TSPAN12 Antibody, HRP conjugated
- 抗体名:
TSPAN12;NET2;TM4SF12;UNQ774/PRO1568;Tetraspanin-12;Tspan-12;Tetraspan NET-2;Transmembrane 4 superfamily member 12
- 规格:
100μg/50μg
| 规格: | 100μg | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥880.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
功能
Regulator of cell surface receptor signal transduction. Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction. Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs. Suprisingly, it only activate the norrin (NDP)-dependent activation of FZD4, while it does not activate the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1) (By similarity). Acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP. Activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP). Activates MMP14/MT1-MMP-dependent cleavage activity.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验TM4SF1:从抗血管新生到免疫逃逸调控,这个四次跨膜蛋白靶点还有多少惊喜?
● Recombinant Macaca fascicularis Transmembrane 4 L6 family member 1 (TM4SF1)-VLPs (Active) Code: CSB-MP5031MOV 华美 CUSABIO TM4SF1 抗体 TM4SF1 Recombinant Monoclonal Antibody (Code: CSB-RA023615MA1HU)
分子质量(kDa)和结构:(IgSF) 功 能:与β2m组成MHCI类样分子,有抗原提呈功能 CD1 Family of non-polymorphic MHC class I-like glycoproteins Also member of immunoglobulin superfamily On chromosome 1q22-23 (not MHC linked) Has 5 different
Nature Aging & Cancer Cell双重磅加持:GFRAL靶点迎来黄金窗口期,三大临床路径全面提速
for survival after myocardial infarction in mice." Nature medicine 17.5 (2011): 581-588. [6] Strelau, J., et al. "GDF-15/MIC-1 a novel member of the TGF-ß superfamily." Advances in Research on Neurodegeneration (2000): 273-276. [7] Mullican, Shannon E
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