- ￥2260
- LSM Bio
- 进口
- PAab09055
- 2025年07月14日
- ELISA,WB
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
tetraspanin 12
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9BZJ3
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
tetraspanin 12
- 抗体英文名：
anti-TSPAN12 antibody,TSPAN12 antibody
- 抗体名：
anti-TSPAN12 抗体,TSPAN12 抗体
- 规格：
100μl
TSPAN12抗体| TSPAN12 antibody
货号 PAab09055
蛋白别名 NET 2 antibody, NET2 antibody, Tetraspan NET 2 antibody, tetraspanin 12 antibody, TM4SF12 antibody, Tspan 12 antibody, TSPAN12
蛋白介绍
Regulator of cell surface receptor signal transduction. Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction. Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs. Suprisingly, it only activate the norrin (NDP)-dependent activation of FZD4, while it does not activate the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1) (By similarity). Acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP. Activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP). Activates MMP14/MT1-MMP-dependent cleavage activity.
产品描述
anti-TSPAN12 antibody is a Rabbit Polyclonal antibody againstTSPAN12..
建议稀释比例
WB : 1:200-1:2000
IHC
Western blot
HepG2 cells were subjected to SDS PAGE followed by western blot with PAab09055(TSPAN12 antibody) at dilution of 1:500(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验
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